Uterine carcinosarcoma: a primer for radiologists
Sign Up to like & getrecommendations! Published in 2019 at "Abdominal Radiology"
DOI: 10.1007/s00261-019-02038-8
Abstract: ObjectiveTo provide a modern overview for radiologists of the unique radiological, pathological, and clinical features of uterine carcinosarcoma (UCS).ResultsUCS is a unique gynecological malignancy that continues to present diagnostic and therapeutic challenges to the field… read more here.
Keywords: clinical features; carcinosarcoma primer; primer radiologists; uterine carcinosarcoma ... See more keywords
Histopathological features of HER2 overexpression in uterine carcinosarcoma: proposal for requirements in HER2 testing for targeted therapy
Sign Up to like & getrecommendations! Published in 2021 at "Virchows Archiv"
DOI: 10.1007/s00428-021-03017-5
Abstract: Uterine carcinosarcoma (UCS) is an uncommon and highly aggressive tumor. There is no HER2 testing protocol for UCS despite the development of HER2 antibody conjugates. We aimed to elucidate histopathological HER2 expression details in UCS,… read more here.
Keywords: her2 testing; features her2; uterine carcinosarcoma; histopathological features ... See more keywords
Patterns of adjuvant treatment and survival outcomes in stage I uterine carcinosarcoma
Sign Up to like & getrecommendations! Published in 2022 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2022.100930
Abstract: Highlights • 5-year survival for stage I uterine carcinosarcoma without adjuvant therapy is 43%.• Nationally 40% of stage I uterine carcinosarcoma do not receive adjuvant therapy.• Adjuvant chemotherapy alone improved OS and CSS in stage… read more here.
Keywords: survival; adjuvant treatment; uterine carcinosarcoma; stage uterine ... See more keywords
Uterine carcinosarcoma associated with a germline nibrin (NBN) mutation
Sign Up to like & getrecommendations! Published in 2022 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2022.100979
Abstract: Highlights • We report a patient with uterine carcinosarcoma associated with a germline NBN mutation.• Tumor also exhibited a high tumor mutational burden (>10 mutations/Mb)• Patient responded to platinum rechallenge, PARP inhibitor maintenance and immunotherapy.•… read more here.
Keywords: nbn mutation; associated germline; uterine carcinosarcoma; carcinosarcoma associated ... See more keywords
Treatment and outcome of patients with uterine carcinosarcoma: Data from developing world.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e18102
Abstract: e18102Background: To evaluate the clinicopathological factors, outcome and prognostics factors of uterine carcinosarcoma. Methods: All patients of uterine carcinosarcoma treated between January 201... read more here.
Keywords: patients uterine; outcome patients; carcinosarcoma data; uterine carcinosarcoma ... See more keywords
Exploring biomarkers and prognostic factors in uterine carcinosarcoma: An insight into L1CAM, CDX2, p53, and MSI status
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0285447
Abstract: Background Uterine Carcinosarcomas (UCS) are a rare type of cancer composed of an admixture of high-grade carcinomatous and sarcomatous elements. Clinicopathological prognostic factors in UCS are well established, but studies that approach the impact of… read more here.
Keywords: prognostic factors; uterine carcinosarcoma; l1cam; cdx2 p53 ... See more keywords
Expression of aurora kinases: Predictor of tumor dissemination in uterine carcinosarcoma.
Sign Up to like & getrecommendations! Published in 2017 at "Histology and histopathology"
DOI: 10.14670/hh-11-834
Abstract: Uterine carcinosarcoma is a rare, aggressive, and biphasic tumor. It comprises carcinomatous and sarcomatous components, and mitosis-associated factors are thought to discriminate these two lesions. Aurora kinases are mitotic enzymes that are highly expressed in… read more here.
Keywords: aurora kinase; expression; uterine carcinosarcoma; aurora kinases ... See more keywords