Volumetric imaging of the developing prepubertal mouse uterine epithelium using light sheet microscopy
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.22973
Abstract: Endometrial or uterine glands secrete substances essential for uterine receptivity to the embryo, implantation, conceptus survival, and growth. Adenogenesis is the process of gland formation within the stroma of the uterus. In the mouse, uterine… read more here.
Keywords: uterine gland; microscopy; gland formation; mouse uterine ... See more keywords
Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
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DOI: 10.1038/s41467-019-13363-3
Abstract: Wnt signaling is critical for directing epithelial gland development within the uterine lining to ensure successful gestation in adults. Wnt-dependent, Lgr5-expressing stem/progenitor cells are essential for the development of glandular epithelia in the intestine and… read more here.
Keywords: uterine gland; wnt dependent; gland development; stem ... See more keywords
Chronic estrus disrupts uterine gland development and homeostasis.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac011
Abstract: Female mice homozygous for an engineered Gnrhr E90K mutation have reduced gonadotropin-releasing hormone signaling, leading to infertility. Their ovaries have numerous antral follicles but no corpora lutea, indicating a block to ovulation. These mutants have… read more here.
Keywords: development; pubertal uterine; post pubertal; gland development ... See more keywords
Pik3ca is required for mouse uterine gland development and pregnancy
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DOI: 10.1371/journal.pone.0191433
Abstract: The PI3K/AKT signaling pathway plays a critical role in the maintenance of equilibrium between cell survival and apoptosis. The Pik3ca gene is mutated in a range of human cancers. It has been found to be… read more here.
Keywords: uterine gland; pik3ca; gland development; gland ... See more keywords
Role of EZH2 in Uterine Gland Development
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DOI: 10.3390/ijms232415665
Abstract: Enhancer of zeste homolog 2 (EZH2) is a core component of polycomb repressive complex 2 that plays a vital role in transcriptional repression of gene expression. Conditional ablation of EZH2 using progesterone receptor (Pgr)-Cre in… read more here.
Keywords: role ezh2; role; uterine gland; development ... See more keywords