MMP14 expression and collagen remodelling support uterine leiomyosarcoma aggressiveness.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13440
Abstract: Fibrillar collagen deposition, stiffness and downstream signalling support the development of leiomyomas (LMs), common benign mesenchymal tumours of the uterus, and are associated with aggressiveness in multiple carcinomas. Compared to epithelial carcinomas, however, the impact… read more here.
Keywords: expression collagen; uterine leiomyosarcoma; collagen; support ... See more keywords
Prognostic factors and survival outcomes of women with uterine leiomyosarcoma: A Turkish Uterine Sarcoma Group Study-003.
Sign Up to like & getrecommendations! Published in 2021 at "Current problems in cancer"
DOI: 10.1016/j.currproblcancer.2021.100712
Abstract: To assess the clinicopathological features, prognostic factors, and survival rates associated with uterine leiomyosarcoma (uLMS). Databases from 15 participating gynecological oncology centers in Turkey were searched retrospectively for women who had been treated for stage… read more here.
Keywords: prognostic factors; figo stage; disease; uterine leiomyosarcoma ... See more keywords
Unexpected Uterine Leiomyosarcoma During Laparoscopic Hysterectomy Treated 6 Months With Ulipristal Acetate and Contained Power Morcellation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of minimally invasive gynecology"
DOI: 10.1016/j.jmig.2016.08.004
Abstract: DESIGN A 45-year-old woman with a symptomatic uterine myoma suffering from heavy menstrual bleeding, incontinence, and pain pressure received ulipristal acetate (UPA [Esmya; Gideon Richter, Budapest, Hungary]) for 6 months. SETTING A Minimal Invasive Gynecology… read more here.
Keywords: ulipristal acetate; uterine leiomyosarcoma; unexpected uterine; laparoscopic hysterectomy ... See more keywords
A Case of Recurrent Uterine Leiomyosarcoma Treated with Complete Laparoscopic Resection
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Minimally Invasive Gynecology"
DOI: 10.1016/j.jmig.2019.09.025
Abstract: Video Objective Uterine leiomyosarcoma (uLMS) is aggressive mesenchymal neoplasm and is associated with a high risk of recurrence and poor prognosis. The 5year overall survival rate is about 60% even in FIGO stage I disease.… read more here.
Keywords: laparoscopic; case recurrent; case; uterine leiomyosarcoma ... See more keywords
Adjuvant gemcitabine-docetaxel chemotherapy for stage I uterine leiomyosarcoma: Trends and survival outcomes.
Sign Up to like & getrecommendations! Published in 2017 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2017.07.122
Abstract: OBJECTIVE To assess recent trends of administering adjuvant gemcitabine-docetaxel (GD) chemotherapy for Stage I uterine leiomyosarcoma, and to compare disease-free and overall survival between women who received and did not receive adjuvant GD chemotherapy. METHODS… read more here.
Keywords: chemotherapy; uterine leiomyosarcoma; stage uterine; adjuvant chemotherapy ... See more keywords
Uterine leiomyosarcoma: A review of the literature and update on management options.
Sign Up to like & getrecommendations! Published in 2018 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2018.09.010
Abstract: Uterine leiomyosarcoma is the most common type of uterine sarcoma. It is an extremely aggressive malignancy associated with a poor overall prognosis. Women affected may vary in age, but are most often diagnosed in their… read more here.
Keywords: management; review literature; uterine leiomyosarcoma; leiomyosarcoma review ... See more keywords
Impact of adjuvant treatment and prognostic factors in stage I uterine leiomyosarcoma patients treated in Commission on Cancer®-accredited facilities.
Sign Up to like & getrecommendations! Published in 2019 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2019.12.008
Abstract: OBJECTIVES Determine the impact of adjuvant chemotherapy (ACT) and prognostic factors in surgically managed patients with stage I uterine leiomyosarcoma (ULMS). METHODS Women who underwent hysterectomy and were diagnosed with stage I ULMS between 2010… read more here.
Keywords: prognostic factors; act act; act; stage uterine ... See more keywords
Proposing the 3-tier staging system for improving prognostication in stage I uterine leiomyosarcoma
Sign Up to like & getrecommendations! Published in 2021 at "Gynecologic Oncology"
DOI: 10.1016/s0090-8258(21)01121-5
Abstract: Objectives: Current cancer staging uses a 2-tier schema for stage I uterine leiomyosarcoma based on tumor size (≤5cm versus >5cm). Given the majority of stage I uterine leiomyosarcomas are >5cm in tumor size, this study… read more here.
Keywords: stage uterine; size; tumor size; uterine leiomyosarcoma ... See more keywords
Surgical and oncologic outcomes of hyperthermic intraperitoneal chemotherapy for uterine leiomyosarcoma
Sign Up to like & getrecommendations! Published in 2021 at "Gynecologic Oncology"
DOI: 10.1016/s0090-8258(21)01184-7
Abstract: Objectives: To examine the perioperative and survival outcomes in women with disseminated peritoneal uterine leiomyosarcoma (uLMS) who underwent cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Methods: A systematic review of literature was performed and… read more here.
Keywords: hyperthermic intraperitoneal; disseminated peritoneal; hipec; uterine leiomyosarcoma ... See more keywords
Unexpected uterine leiomyosarcoma in a woman with multiple myomas treated with ulipristal acetate: case report and literature review
Sign Up to like & getrecommendations! Published in 2018 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2017.1380186
Abstract: Abstract Ulipristal acetate (UPA) has been recognized as an alternative strategy to surgery in the management of symptomatic women with uterine fibroids. We present a case report on a woman with hereditary fibrinogen deficiency exclusively… read more here.
Keywords: uterine leiomyosarcoma; leiomyosarcoma; multiple myomas; case report ... See more keywords
Diffusion-Weighted Imaging for Differentiating Uterine Leiomyosarcoma From Degenerated Leiomyoma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Computer Assisted Tomography"
DOI: 10.1097/rct.0000000000000565
Abstract: Purpose The study aimed to investigate magnetic resonance diffusion-weighted imaging (DWI) in the differentiation of uterine leiomyosarcoma (ULMS) from degenerated leiomyoma (DLM). Methods Sixteen patients with ULMSs and 26 patients with DLMs confirmed by surgery… read more here.
Keywords: degenerated leiomyoma; diffusion; weighted imaging; uterine leiomyosarcoma ... See more keywords