Increased cocaine and amphetamine-regulated transcript cord blood levels in the newborns exposed to crack cocaine in utero
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4759-6
Abstract: BackgroundCocaine and amphetamine-regulated transcript (CART) is an endogenous antioxidant present since the embryonic period. CART is activated by high levels of dopamine and might be of interested in understanding the changes in the REDOX system… read more here.
Keywords: cart; utero; cart levels; crack cocaine ... See more keywords
In utero exposure to electronic-cigarette aerosols decreases lung fibrillar collagen content, increases Newtonian resistance and induces sex-specific molecular signatures in neonatal mice
Sign Up to like & getrecommendations! Published in 2021 at "Toxicological Research"
DOI: 10.1007/s43188-021-00103-3
Abstract: Approximately 7% of pregnant women in the United States use electronic-cigarette (e-cig) devices during pregnancy. There is, however, no scientific evidence to support e-cig use as being ‘safe’ during pregnancy. Little is known about the… read more here.
Keywords: cig; utero; utero exposure; collagen content ... See more keywords
Severe drought exposure in utero associates to children’s epigenetic age acceleration in a global climate change hot spot
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DOI: 10.1038/s41467-024-48426-7
Abstract: The goal of this study is to examine the association between in utero drought exposure and epigenetic age acceleration (EAA) in a global climate change hot spot. Calculations of EAA in adults using DNA methylation… read more here.
Keywords: drought; climate change; global climate; utero ... See more keywords
In utero rescue of neurological dysfunction in a mouse model of Wiedemann-Steiner syndrome
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DOI: 10.1101/2024.07.19.604339
Abstract: Wiedemann-Steiner syndrome (WDSTS) is a rare genetic cause of intellectual disability primarily caused by heterozygous loss of function variants in the gene encoding the histone methyltransferase KMT2A. Prior studies have shown successful postnatal amelioration of… read more here.
Keywords: steiner syndrome; mouse model; utero; mouse ... See more keywords
In utero exposure to valproic acid throughout pregnancy causes phenotypes of autism in offspring mice.
Sign Up to like & getrecommendations! Published in 2023 at "Developmental neuroscience"
DOI: 10.1159/000530452
Abstract: Valproic acid (VPA) is an antiepileptic drug that inhibits the epileptic activity of neurons mainly by inhibiting sodium channels and GABA transaminase. VPA is also known to inhibit histone deacetylases, which epigenetically modify the cell… read more here.
Keywords: throughout pregnancy; utero; valproic acid; exposure ... See more keywords
Neurodevelopment in Normocephalic Children Exposed to Zika Virus in Utero with No Observable Defects at Birth: A Systematic Review with Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19127319
Abstract: Zika virus (ZIKV) infection during pregnancy is a cause of pregnancy loss and multiple clinical and neurological anomalies in children. This systematic review aimed to assess the effect of ZIKV exposure in utero on the… read more here.
Keywords: review; normocephalic children; systematic review; neurodevelopment normocephalic ... See more keywords