Utility of comprehensive genomic profiling (CGP) for personal cancer vaccine development via neoantigen analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.3100
Abstract: 3100Background: Cancer vaccines against neoantigens have shown promise in treating advanced stage cancers [1,2]. Typically, detection of somatic mutations underlying neoantigen expression is done u... read more here.
Keywords: comprehensive genomic; utility comprehensive; cgp personal; genomic profiling ... See more keywords
Clinical utility of comprehensive genomic pathway and integrated network analyses in personalized oncology.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e14051
Abstract: e14051Background: Adoption of next-generation sequencing (NGS) technology in routine clinical practice has enabled the detection of genetic aberrations such as single nucleotide variants, copy numb... read more here.
Keywords: utility comprehensive; comprehensive genomic; clinical utility; oncology clinical ... See more keywords
Clinical utility of comprehensive genomic profiling and targeted therapy in biliary tract cancers: A real-world experience.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e16671
Abstract: e16671Background: Biliary tract cancers (BTC) are a highly aggressive group of malignancies with high mortality and poor prognosis. Chemotherapy is the mainstay of treatment for advanced disease. T... read more here.
Keywords: biliary tract; comprehensive genomic; utility comprehensive; clinical utility ... See more keywords
Clinical utility of comprehensive genomic profiling in Japan: Result of PROFILE-F study
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DOI: 10.1371/journal.pone.0266112
Abstract: Introduction Clinical sequencing has provided molecular and therapeutic insights into the field of clinical oncology. However, despite its significance, its clinical utility in Japanese patients remains unknown. Here, we examined the clinical utility of tissue-based… read more here.
Keywords: clinical sequencing; foundationone; clinical utility; utility comprehensive ... See more keywords