SNPs in 3'-UTR region of MBL2 increases susceptibility to recurrent vulvovaginal infections by altering sMBL levels.
Sign Up to like & getrecommendations! Published in 2019 at "Immunobiology"
DOI: 10.1016/j.imbio.2018.10.009
Abstract: Recurrent vulvovaginal infections (RVVI), owing to their adverse health consequences, have become a serious dilemma worldwide. Low serum levels of Mannose-Binding Lectin (sMBL), a main component of innate immunity, was found to be associated with… read more here.
Keywords: risk; smbl levels; recurrent vulvovaginal; vulvovaginal infections ... See more keywords
Investigation of UTR Variants by Computational Approaches Reveal Their Functional Significance in PRKCI Gene Regulation
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14020247
Abstract: Single nucleotide polymorphisms (SNPs) are associated with many diseases including neurological disorders, heart diseases, diabetes, and different types of cancers. In the context of cancer, the variations within non-coding regions, including UTRs, have gained utmost… read more here.
Keywords: utr region; prkci gene; investigation utr; prkci ... See more keywords