Hydroxyphenylpyruvate dioxygenase is a metabolic immune checkpoint for UTX-deficient colorectal cancer.
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DOI: 10.1053/j.gastro.2023.02.010
Abstract: BACKGROUND & AIMS Aberrant epigenetic events mediated by histone methyltransferases and demethylases contributes to malignant progression of colorectal cancer (CRC). However, the role of the histone demethylase ubiquitously transcribed tetratricopeptide repeat on chromosome X (UTX)… read more here.
Keywords: crc; hydroxyphenylpyruvate dioxygenase; colorectal cancer; utx deficient ... See more keywords