UVA-induced photoaging inhibits autophagic degradation by impairing lysosomal function in dermal fibroblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.08.103
Abstract: Autophagy has been associated with a variety of diseases especially aging. Human dermal fibroblasts (HDFs) can internalize and then degrade elastin, collagen and advanced glycation end products (AGEs) in lysosomes, which plays prominent roles in… read more here.
Keywords: degradation; uva induced; induced photoaging; photoaged fibroblasts ... See more keywords
The protective effect of hesperetin on UVA-induced matrix metalloproteinase-1 (MMP-1) in primary human dermal fibroblasts and mouse skin through modulation of nuclear factor erythroid 2- related factor 2 (NRF2)-regulated antioxidant defenses
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.04.127
Abstract: Skin aging is an accumulation of collagen degradation caused by matrix metalloproteinase-1 (MMP-1) mainly present in human dermal fibroblasts (HDFs). Increased activity of Nrf2, the transcription factor of antioxidant genes, to counteract oxidative stress is… read more here.
Keywords: uva induced; antioxidant defenses; mouse skin; mmp ... See more keywords
The UVA-induced long non-coding RNA GS1-600G8.5 regulates the expression of IL-8.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2018.02.013
Abstract: [1] H. Vanbokhoven, G. Melino, E. Candi, W. Declercq, p63, a story of mice and men, J. Invest. Dermatol. 131 (2011) 1196–1207. [2] J. Celli, P. Duijf, B.C. Hamel, M. Bamshad, B. Kramer, A.P. Smits,… read more here.
Keywords: uva induced; induced long; rna gs1; long non ... See more keywords
Akt activation‐dependent protective effect of wild ginseng adventitious root protein against UVA‐induced NIH‐3T3 cell damage
Sign Up to like & getrecommendations! Published in 2021 at "Wound Repair and Regeneration"
DOI: 10.1111/wrr.12962
Abstract: Prolonged skin exposure to ultraviolet radiation can lead to development of several acute and chronic diseases, with UVA exposure considered a primary cause of dermal photodamage. We prepared a wild ginseng adventitious root extract (ARE)… read more here.
Keywords: uva induced; cell; nih 3t3; induced nih ... See more keywords
Ceria Nanoparticles Decrease UVA-Induced Fibroblast Death Through Cell Redox Regulation Leading to Cell Survival, Migration and Proliferation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.577557
Abstract: Exposure to ultraviolet radiation is a major contributor to premature skin aging and carcinogenesis, which is mainly driven by overproduction of reactive oxygen species (ROS). There is growing interest for research on new strategies that… read more here.
Keywords: survival migration; uva induced; cell survival; proliferation ... See more keywords
Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00691
Abstract: Purified vitexin compound 1 (VB1), a novel lignanoid isolated from the seeds of the Chinese herb Vitex negundo, has strong antioxidant abilities and broad antitumor activities. However, little is known about its anti-photoaging effect on… read more here.
Keywords: uva induced; human dermal; vitexin compound; purified vitexin ... See more keywords
The Effect of Carnosine on UVA-Induced Changes in Intracellular Signaling of Human Skin Fibroblast Spheroids
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020300
Abstract: Dermis fibroblasts are very sensitive to penetrating UVA radiation and induce photo-damage. To protect skin cells against this environmental damage, there is an urgent need for effective compounds, specifically targeting UVA-induced mitochondrial injury. This study… read more here.
Keywords: carnosine; uva induced; human skin; effect carnosine ... See more keywords
Protection against Ultraviolet A-Induced Skin Apoptosis and Carcinogenesis through the Oxidative Stress Reduction Effects of N-(4-bromophenethyl) Caffeamide, a Propolis Derivative
Sign Up to like & getrecommendations! Published in 2020 at "Antioxidants"
DOI: 10.3390/antiox9040335
Abstract: Ultraviolet A (UVA) is a major factor in skin aging and damage. Antioxidative materials may ameliorate this UV damage. This study investigated the protective properties of N-(4-bromophenethyl) caffeamide (K36H) against UVA-induced skin inflammation, apoptosis and… read more here.
Keywords: uva induced; k36h; apoptosis; induced skin ... See more keywords
Antiphotoaging Effect of (2′S)-Columbianetin from Corydalis heterocarpa in UVA-Irradiated Human Dermal Fibroblasts
Sign Up to like & getrecommendations! Published in 2020 at "Applied Sciences"
DOI: 10.3390/app10072568
Abstract: Ultraviolet A (UVA)-induced detrimental effects in the skin, also known as photoaging, are mediated with several pathways including oxidative stress generation and extracellular matrix (ECM) degradation. UVA irradiation results in excessive production of matrix metalloproteinases… read more here.
Keywords: human dermal; uva induced; columbianetin; corydalis heterocarpa ... See more keywords
Protective Effects and Mechanisms of N-Phenethyl Caffeamide from UVA-Induced Skin Damage in Human Epidermal Keratinocytes through Nrf2/HO-1 Regulation
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20010164
Abstract: The skin provides an effective barrier against physical, chemical, and microbial invasion; however, overexposure to ultraviolet (UV) radiation causes excessive cellular oxidative stress, which leads to skin damage, DNA damage, mutations, and skin cancer. This… read more here.
Keywords: uva induced; protective effects; damage; phenethyl caffeamide ... See more keywords
Protective Effect of l-Hexaguluroic Acid Hexasodium Salt on UVA-Induced Photo-Aging in HaCaT Cells
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21041201
Abstract: This study aimed to show the α-l-Hexaguluroic acid hexasodium salt (G6) protective effect against UVA-induced photoaging of human keratinocyte cells. We found that G6 localized to the mitochondria and improved mitochondrial functions. G6 increased respiratory… read more here.
Keywords: uva induced; uva; hexaguluroic acid; protective effect ... See more keywords