miR-216b enhances the efficacy of vemurafenib by targeting Beclin-1, UVRAG and ATG5 in melanoma.
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DOI: 10.1016/j.cellsig.2017.09.024
Abstract: Autophagy maintains cells survival in many stressful conditions including starvation, growth factor deprivation and misfolded protein accumulation. Additionally, autophagic survival mechanisms are used by transformed tumor cells to inhibit cell death, limit drug effectiveness and… read more here.
Keywords: melanoma; mir 216b; drug; uvrag atg5 ... See more keywords