Articles with "v117957" as a keyword



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0198 Psychomotor/Cognitive Effects, Pharmacokinetics and Safety of V117957, a Novel, Highly Potent and Selective Partial Agonist for Nociceptin/Orphanin-FQ Peptide (NOP) Receptors, Administered in Combination with Alcohol in Healthy Subjects

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Published in 2020 at "Sleep"

DOI: 10.1093/sleep/zsaa056.196

Abstract: V117957 is an investigational nociceptin/orphanin-FQ peptide (NOP) receptor partial agonist designed to treat insomnia by promoting sleep onset and maintenance with minimal residual next-day somnolence or psychomotor impairment. The satisfactory safety/tolerability profile of V117957 has… read more here.

Keywords: safety; psychomotor cognitive; healthy subjects; v117957 ... See more keywords