Insights into Allosteric Mechanisms of the Lung-Enriched p53 Mutants V157F and R158L
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DOI: 10.3390/ijms231710100
Abstract: Lung cancer is a leading fatal malignancy in humans. p53 mutants exhibit not only loss of tumor suppressor capability but also oncogenic gain-of-function, contributing to lung cancer initiation, progression and therapeutic resistance. Research shows that… read more here.
Keywords: insights allosteric; p53 mutants; lung; v157f r158l ... See more keywords