V2a interneuron differentiation from mouse and human pluripotent stem cells
Sign Up to like & getrecommendations! Published in 2019 at "Nature Protocols"
DOI: 10.1038/s41596-019-0203-1
Abstract: V2a interneurons are located in the hindbrain and spinal cord, where they provide rhythmic input to major motor control centers. Many of the phenotypic properties and functions of excitatory V2a interneurons have yet to be… read more here.
Keywords: human pluripotent; v2a interneurons; mouse human; pluripotent stem ... See more keywords
Anatomical Recruitment of Spinal V2a Interneurons into Phrenic Motor Circuitry after High Cervical Spinal Cord Injury.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of neurotrauma"
DOI: 10.1089/neu.2017.5045
Abstract: More than half of all spinal cord injuries (SCIs) occur at the cervical level, often resulting in impaired respiration. Despite this devastating outcome, there is substantial evidence for endogenous neuroplasticity after cervical SCI. Spinal interneurons… read more here.
Keywords: high cervical; v2a interneurons; spinal cord; phrenic motor ... See more keywords
Chx10+V2a interneurons in spinal motor regulation and spinal cord injury
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.355746
Abstract: Chx10-expressing V2a (Chx10+V2a) spinal interneurons play a large role in the excitatory drive of motoneurons. Chemogenetic ablation studies have demonstrated the essential nature of Chx10+V2a interneurons in the regulation of locomotor initiation, maintenance, alternation, speed,… read more here.
Keywords: chx10 v2a; cord injury; v2a interneurons; spinal cord ... See more keywords