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Published in 2019 at "Nature Protocols"
DOI: 10.1038/s41596-019-0203-1
Abstract: V2a interneurons are located in the hindbrain and spinal cord, where they provide rhythmic input to major motor control centers. Many of the phenotypic properties and functions of excitatory V2a interneurons have yet to be…
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Keywords:
human pluripotent;
v2a interneurons;
mouse human;
pluripotent stem ... See more keywords
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Published in 2017 at "Journal of neurotrauma"
DOI: 10.1089/neu.2017.5045
Abstract: More than half of all spinal cord injuries (SCIs) occur at the cervical level, often resulting in impaired respiration. Despite this devastating outcome, there is substantial evidence for endogenous neuroplasticity after cervical SCI. Spinal interneurons…
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Keywords:
high cervical;
v2a interneurons;
spinal cord;
phrenic motor ... See more keywords
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Published in 2025 at "Journal of neurotrauma"
DOI: 10.1177/08977151251386031
Abstract: Spinal cord injuries (SCI) are extremely difficult to treat due to the limited capacity for neural regeneration across the injury site. However, V2a interneurons have been a point of interest in SCI research over the…
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Keywords:
spinal cord;
v2a interneurons;
site;
regeneration spinal ... See more keywords
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Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.355746
Abstract: Chx10-expressing V2a (Chx10+V2a) spinal interneurons play a large role in the excitatory drive of motoneurons. Chemogenetic ablation studies have demonstrated the essential nature of Chx10+V2a interneurons in the regulation of locomotor initiation, maintenance, alternation, speed,…
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Keywords:
chx10 v2a;
cord injury;
v2a interneurons;
spinal cord ... See more keywords