TLR2 and 4 signaling pathways are altered in macrophages from V30M TTR mice with downregulated expression of chemokines.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical science"
DOI: 10.1042/cs20220656
Abstract: Hereditary transthyretin amyloidosis (ATTRv) is a fatal neurodegenerative disorder, firstly identified in Portugal. The most common TTR mutation in ATTRv results from an exchange of a methionine for a valine at position 30 (V30M). ATTRv… read more here.
Keywords: ttr mice; expression; v30m ttr; tlr2 signaling ... See more keywords