Oncogenic non-V600 mutations evade the regulatory machinery of RAF including the Cdc37/Hsp90 chaperone and the 14-3-3 scaffold
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DOI: 10.7150/thno.103958
Abstract: The Ser/Thr kinase RAF, particularly BRAF isoform is a dominant target of oncogenic mutations and many mutations have been identified in various cancers. However, how these mutations except V600E evade the regulatory machinery of RAF… read more here.
Keywords: regulatory machinery; non v600; cdc37 hsp90; v600 mutations ... See more keywords