Survival Outcomes of Resected BRAF V600E Mutant Colorectal Liver Metastases: A Multicenter Retrospective Cohort Study in Japan
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-020-08817-8
Abstract: Although the prognosis for patients with resected BRAF mutant colorectal liver metastases (CRLM) is poor, the survival impact of the BRAF V600E mutation in such cases remains unclear. A multicenter retrospective cohort study was performed… read more here.
Keywords: braf v600e; resected braf; study; v600e ... See more keywords
BRAF-V600E mutant papillary craniopharyngioma dramatically responds to combination BRAF and MEK inhibitors.
Sign Up to like & getrecommendations! Published in 2017 at "CNS oncology"
DOI: 10.2217/cns-2016-0034
Abstract: We present a patient with BRAF-V600E mutant papillary craniopharyngioma successfully treated with combination BRAF (dabrafenib 150 mg twice daily) and MEK (trametinib 2 mg daily) inhibitors after her unresectable tumor proved refractory to radiation. Serial… read more here.
Keywords: braf v600e; mutant papillary; braf; combination braf ... See more keywords
Identification of BRAF p. V600E-Mutant and Wild-Type by MR Imaging in Pleomorphic Xanthoastrocytoma and Anaplastic Pleomorphic Xanthoastrocytoma
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DOI: 10.3174/ajnr.a7324
Abstract: BACKGROUND AND PURPOSE: Compared with BRAF p. V600E wild-type pleomorphic xanthoastrocytoma, BRAF p. V600E-mutant pleomorphic xanthoastrocytoma showed a higher survival rate. In this study, we focused on finding preoperative MR imaging differences between BRAF p.… read more here.
Keywords: v600e mutant; pleomorphic xanthoastrocytoma; xanthoastrocytoma; anaplastic pleomorphic ... See more keywords