An Odyssey into the Land of Deleterious Rare Mutations in Colorectal Liver Metastases
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-020-08820-z
Abstract: In this issue, Kobayashi et al. present the survival of patients with BRAF V600E mutations who underwent initial hepatectomy for colorectal liver metastases (CLM) from 2005 to 2016 at six high-volume institutions in Japan. Among… read more here.
Keywords: chemotherapy; v600e mutations; non v600e; oncology ... See more keywords
Evaluation of molecular diagnostic approaches for the detection of BRAF p.V600E mutations in papillary thyroid cancer: Clinical implications
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179691
Abstract: Differentiated papillary thyroid cancer (PTC) is the most common cancer of the endocrine system. PTC has a very good prognosis and a high 5 year survival rate; however, some patients are unresponsive to treatment, and… read more here.
Keywords: braf v600e; detection; v600e mutations; braf ... See more keywords
Expanding the Spectrum of BRAF Non-V600E Mutations in Thyroid Nodules: Evidence-Based Data from a Tertiary Referral Centre
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DOI: 10.3390/ijms24044057
Abstract: The BRAF p.V600E mutation represents the most specific marker for papillary thyroid carcinoma and is potentially related to aggressive behavior and persistent disease. BRAF alterations other than the p.V600E are less common in thyroid carcinoma… read more here.
Keywords: thyroid; non v600e; braf non; v600e mutations ... See more keywords
ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations
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DOI: 10.3390/toxins13020146
Abstract: Melanoma is the main cause of skin cancer deaths, with special emphasis in those cases carrying BRAF mutations that trigger the mitogen-activated protein kinases (MAPK) signaling and unrestrained cell proliferation in the absence of mitogens.… read more here.
Keywords: braf v600e; v600e mutations; melanoma braf; v600e ... See more keywords