BRAF activating mutations involving the β3-αC loop in V600E-negative anaplastic pleomorphic xanthoastrocytoma
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DOI: 10.1186/s40478-018-0525-1
Abstract: Anaplastic pleomorphic xanthoastrocytoma (A-PXA, WHO grade III) is a newly defined entity with highgrade histopathologic features and a propensity for recurrence [6]. While PXA with low-grade histology (WHO grade II) can harbor a recurrent valine-toglutamic… read more here.
Keywords: v600e negative; braf; kinase domain; anaplastic pleomorphic ... See more keywords