A HRM assay for identification of low level BRAF V600E and V600K mutations using the CADMA principle in FFPE specimens.
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DOI: 10.1016/j.pathol.2017.08.011
Abstract: Melanoma patients with BRAF V600E and V600K mutations show complete or partial response to vemurafenib. Detection assays often scan for the common V600E mutation rather than the rare V600K variant, although this mutation can be… read more here.
Keywords: v600e v600k; level; v600k mutations; v600e ... See more keywords