Articles with "v617f knockin" as a keyword



Phenformin increases early hematopoietic progenitors in the Jak2V617F murine model

Sign Up to like & get
recommendations!
Published in 2022 at "Investigational New Drugs"

DOI: 10.1007/s10637-022-01212-y

Abstract: Background.  Myeloproliferative neoplasms (MPN) are disorders characterized by an alteration at the hematopoietic stem cell (HSC) level, where the JAK2 mutation is the most common genetic alteration found in classic MPN (polycythemia vera, essential thrombocythemia,… read more here.

Keywords: jak2; jak2 v617f; phenformin; early hematopoietic ... See more keywords