The relationship between JAK2(V617F) mutation and dermatomyositis—a case report and literature review
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-05286-y
Abstract: The JAK family (JAK1, JAK2, JAK3, and TYK2) have recently emerged as a potential therapeutic management in controlling severe and refractory dermatomyositis. Meanwhile, the progress in the discovery of JAK blockers is significant, with an… read more here.
Keywords: dermatomyositis; v617f mutation; jak2 v617f; case ... See more keywords
High prevalence of heparin induced thrombocytopenia with thrombosis among patients with essential thrombocytemia carrying V617F mutation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-017-1566-1
Abstract: Arterial and venous complications are major causes of morbidity and mortality in myeloproliferative neoplasms (MPNs). MPNs patients, frequently receive heparin. Heparin-induced thrombocytopenia (HIT) is a rare but potentially life-threatening complication resulting in a severe acquired… read more here.
Keywords: heparin treatment; v617f mutation; induced thrombocytopenia; heparin induced ... See more keywords
Successful treatment for a patient with chronic thromboembolic pulmonary hypertension comorbid with essential thrombocythemia with the JAK2 V617F mutation by balloon pulmonary angioplasty
Sign Up to like & getrecommendations! Published in 2020 at "Respiratory Medicine Case Reports"
DOI: 10.1016/j.rmcr.2020.101235
Abstract: A-71-year-old woman was diagnosed as chronic thromboembolic pulmonary hypertension (CTEPH) accompanied by essential thrombocythemia (ET) with JAK2 V617F mutation. Blood test showed remarkable increase of platelet counts (132.9 × 10^4/μL) and elevated plasma BNP level… read more here.
Keywords: jak2 v617f; chronic thromboembolic; v617f mutation;
AB0825 JAK2 (V617F) MUTATION AND ASSOCIATION TO IMMUNE MEDIATED DISEASES. STUDY OF 130 PATIENTS FROM A SINGLE UNIVERSITY HOSPITAL
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-eular.2161
Abstract: Janus Kinases (JAK) are tirosin-kinases that can promote cytokine production in immune and hematopoietic cells. The JAK-2 (V617F) mutation is the most frequently detected mutation in myeloproliferative neoplasms (MPN) which include essential thrombocythemia (ET), polycythemia… read more here.
Keywords: mediated diseases; immune mediated; v617f mutation; mutation ... See more keywords
Central Nervous System Lymphoma Harboring the JAK2 V617F Mutation That Developed after a 20-year History of Polycythemia Vera
Sign Up to like & getrecommendations! Published in 2018 at "Internal Medicine"
DOI: 10.2169/internalmedicine.1093-18
Abstract: A 78-year-old man who had a 20-year history of polycythemia vera (PV) with a JAK2 V617F mutation presented with gradually progressive disturbance of consciousness. Hyper-intense lesions in the peri-lateral ventricular area and left cerebellar hemisphere… read more here.
Keywords: jak2 v617f; year; v617f mutation;
Myeloid neoplasms with isolated del(5q) and JAK2 V617F mutation: a “grey zone” combination of myelodysplastic and myeloproliferative features?
Sign Up to like & getrecommendations! Published in 2019 at "Haematologica"
DOI: 10.3324/haematol.2019.227686
Abstract: Myelodysplastic syndrome (MDS) with isolated del(5q) [MDS del(5q)] is a World Health Organization (WHO)recognized MDS entity. It is characterized by an interstitial deletion on chromosome 5q occurring either in isolation or with one additional cytogenetic… read more here.
Keywords: jak2 v617f; del; mds; v617f mutation ... See more keywords
Thrombotic incidents in patients with myelofibrosis suggest to be independent of JAK2 V617f mutational status.
Sign Up to like & getrecommendations! Published in 2022 at "Folia medica"
DOI: 10.3897/folmed.64.e72175
Abstract: INTRODUCTION Myelofibrosis (MF) belongs to a group of conditions known as Philadelphia-negative myeloproliferative neoplasms (MPN). Bleeding or various vascular complications could be the main causes of morbidity and mortality in patients with MF. MPNrelated thrombosis… read more here.
Keywords: incidents patients; v617f mutation; thrombotic incidents; jak2 ... See more keywords
Morphologic and Molecular Characteristics of De Novo AML With JAK2 V617F Mutation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the National Comprehensive Cancer Network : JNCCN"
DOI: 10.6004/jnccn.2017.0106
Abstract: Background:JAK2 V617F mutation (mut) in acute myeloid leukemia (AML) is rare. We describe the clinicopathologic findings of a single-institution series of 11 de novo AML cases with JAK2 V617. Methods: We identified cases of de… read more here.
Keywords: jak2 v617f; v617f mutation; novo aml; aml ... See more keywords