Crystal structure of EGFR T790M/C797S/V948R in complex with EAI045.
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DOI: 10.1016/j.bbrc.2018.05.154
Abstract: Lung cancer is the leading cause of cancer deaths. Epidermal growth factor receptor (EGFR) kinase domain mutations are a common cause of non-small cell lung cancers (NSCLCs), a major subtype of lung cancers. Patients harboring… read more here.
Keywords: structure; egfr t790m; v948r complex; t790m c797s ... See more keywords