Preimmunization with a heat-killed preparation of Mycobacterium vaccae enhances fear extinction in the fear-potentiated startle paradigm
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.08.014
Abstract: The hygiene hypothesis or "Old Friends" hypothesis proposes that inflammatory diseases are increasing in modern urban societies, due in part to reduced exposure to microorganisms that drive immunoregulatory circuits, and a failure to terminate inappropriate… read more here.
Keywords: acoustic startle; fear; extinction; fear potentiated ... See more keywords
Evidence that preimmunization with a heat-killed preparation of Mycobacterium vaccae reduces corticotropin-releasing hormone mRNA expression in the extended amygdala in a fear-potentiated startle paradigm
Sign Up to like & getrecommendations! Published in 2019 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2018.12.015
Abstract: Posttraumatic stress disorder (PTSD) is a trauma and stressor-related disorder that is characterized by dysregulation of glucocorticoid signaling, chronic low-grade inflammation, and impairment in the ability to extinguish learned fear. Corticotropin-releasing hormone (Crh) is a… read more here.
Keywords: preimmunization; fear; corticotropin releasing; vaccae ... See more keywords
Regulation of γδT17 cells by Mycobacterium vaccae through interference with Notch/Jagged1 signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Brazilian Journal of Medical and Biological Research"
DOI: 10.1590/1414-431x20209551
Abstract: The objective of this study was to investigate the effect of Mycobacterium vaccae on Jagged 1 and gamma delta T17 (γδT17) cells in asthmatic mice. An asthma mouse model was established through immunization with ovalbumin… read more here.
Keywords: notch; vaccae; t17 cells; t17 ... See more keywords