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Published in 2019 at "Immunity"
DOI: 10.1016/j.immuni.2019.10.008
Abstract: Summary The elicitation of broadly neutralizing antibodies (bNAbs) against the HIV-1 envelope glycoprotein (Env) trimer remains a major vaccine challenge. Most cross-conserved protein determinants are occluded by self-N-glycan shielding, limiting B cell recognition of the…
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Keywords:
envelope;
trimer;
neutralizing antibodies;
vaccination glycan ... See more keywords