UTI patients have pre-existing antigen-specific antibody titers against UTI vaccine antigens.
Sign Up to like & getrecommendations! Published in 2019 at "Vaccine"
DOI: 10.1016/j.vaccine.2019.07.031
Abstract: Urinary tract infection (UTI) is most frequently caused by uropathogenic Escherichia coli (UPEC). Our laboratory has been developing an experimental vaccine targeting four UPEC outer membrane receptors involved in iron acquisition - IreA, FyuA, IutA,… read more here.
Keywords: pre existing; antigen specific; vaccine antigens; vaccine ... See more keywords
Conserved metabolic enzymes as vaccine antigens for giardiasis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010323
Abstract: Giardia lamblia is a leading protozoal cause of diarrheal disease worldwide. Infection is associated with abdominal pain, malabsorption and weight loss, and protracted post-infectious syndromes. A human vaccine is not available against G. lamblia. Prior… read more here.
Keywords: immunization; conserved metabolic; metabolic enzymes; vaccine antigens ... See more keywords
Reduced Placental Transfer of Antibodies Against a Wide Range of Microbial and Vaccine Antigens in HIV-Infected Women in Mozambique
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DOI: 10.3389/fimmu.2021.614246
Abstract: Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency… read more here.
Keywords: vaccine antigens; placental transfer; transfer; transfer antibodies ... See more keywords
Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.964645
Abstract: Vaccine development against Tuberculosis is a strong need, given the low efficacy of the sole vaccine hitherto used, the Bacillus Calmette–Guérin (BCG) vaccine. The chaperone-like protein HtpGMtb of M. tuberculosis is a large dimeric and… read more here.
Keywords: based design; tuberculosis; vaccine antigens; vaccine ... See more keywords