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Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202209624
Abstract: Lipid nanoparticles (LNPs) have proven a successful platform for the delivery of nucleic acid (NA)‐based therapeutics and vaccines, with the ionizable lipid component playing a key role in modulating potency and tolerability. Here, a library…
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Keywords:
unsaturated trialkyl;
ionizable lipids;
vaccine applications;
trialkyl ionizable ... See more keywords
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Published in 2022 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2022.114294
Abstract: Vaccines have been highly successful in the management of many diseases. However, there are still numerous illnesses, both infectious and noncommunicable, for which there are no clinically approved vaccine formulations. While there are unique difficulties…
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Keywords:
nanotechnology;
membrane vesicles;
bacterial membrane;
vaccine applications ... See more keywords