Vaccine Design Against Leptospirosis Using an Immunoinformatic Approach.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0389-5_7
Abstract: Vaccination is the best way to prevent the spread of emerging or reemerging infectious disease. Current research for vaccine development is mainly focused on recombinant-, subunit-, and peptide-based vaccine. At this point, immunoinformatics has been… read more here.
Keywords: vaccine design; design leptospirosis; using immunoinformatic; vaccine candidates ... See more keywords
Vaccines and drugs under clinical trials for prevention and treatment of COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "VirusDisease"
DOI: 10.1007/s13337-020-00650-7
Abstract: The uncertainty related to prevention and treatment of Coronavirus disease 2019 due to lack of effective vaccine candidates or drug molecules has resulted in extensive spread of infection and mortality worldwide. Although the asymptomatic or… read more here.
Keywords: vaccines drugs; clinical trials; prevention treatment; vaccine candidates ... See more keywords
Subtractive proteomics assisted therapeutic targets mining and designing ensemble vaccine against Candida auris for immune response induction
Sign Up to like & getrecommendations! Published in 2022 at "Computers in Biology and Medicine"
DOI: 10.1016/j.compbiomed.2022.105462
Abstract: The emergence of variants and the reports of co-infection caused by Candida auris in COVID-19 patients adds a further complication to the global pandemic situation. To date, no effective therapy is available for C. auris… read more here.
Keywords: proteomics assisted; therapeutic targets; candida auris; vaccine candidates ... See more keywords
New putative vaccine candidates against Acinetobacter baumannii using the reverse vaccinology method.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2020.104114
Abstract: Infections caused by multi-drug resistance Acinetobacter baumannii are increasing worldwide. Discovery of the vaccine against this bacterium as a cost-effective and preventive strategy seems necessary. This study has introduced 11 new putative vaccine candidates against… read more here.
Keywords: baumannii using; new putative; vaccine candidates; vaccine ... See more keywords
A novel staphylococcal enterotoxin B subunit vaccine candidate elicits protective immune response in a mouse model
Sign Up to like & getrecommendations! Published in 2017 at "Toxicon"
DOI: 10.1016/j.toxicon.2017.03.012
Abstract: ABSTRACT Staphylococcal enterotoxin B (SEB), produced by the gram‐positive bacterium Staphylococcus aureus, is responsible for food poisoning and toxic shock syndrome, and is considered a potential bioterrorism agent. Unfortunately, still now no approved vaccines are… read more here.
Keywords: staphylococcal enterotoxin; seb; vaccine candidates; vaccine ... See more keywords
ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.05.032
Abstract: Abstract The Middle East respiratory syndrome coronavirus (MERS-CoV) has infected more than 1900 humans, since 2012. The syndrome ranges from asymptomatic and mild cases to severe pneumonia and death. The virus is believed to be… read more here.
Keywords: chadox1 mva; chadox1 mers; mers cov; vaccine candidates ... See more keywords
Extensive genomic recoding by codon-pair deoptimization selective for mammals is a flexible tool to generate attenuated vaccine candidates for dengue virus 2.
Sign Up to like & getrecommendations! Published in 2019 at "Virology"
DOI: 10.1016/j.virol.2019.09.003
Abstract: The four serotypes of dengue virus (DENV) are the leading etiologic agent of disease caused by arthropod-borne viruses (arboviruses) in the world, with billions at risk of DENV infection spread by infected mosquitoes. DENV causes… read more here.
Keywords: codon; codon pair; dengue virus; vaccine candidates ... See more keywords
Quantum Chemical and Molecular Dynamics Studies of MUC1 Calix[4, 8]arene Scaffold Based Anticancer Vaccine Candidates
Sign Up to like & getrecommendations! Published in 2020 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.9b00989
Abstract: Functional antitumor vaccine constructs are the basis for active tumor immunotherapy, which is useful in the treatment of many types of cancers. MUC1 is one key protein for targeting and designing new strategies for multi-component… read more here.
Keywords: calix arene; quantum chemical; molecular dynamics; chemical molecular ... See more keywords
Peptide-free Synthetic Nicotine Vaccine Candidates with α-Galactosylceramide as Adjuvant.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b01095
Abstract: Peptides are generally needed as T-helper epitopes in nicotine vaccines to induce effective antibody responses, but the highly polymorphic property of major histocompatibility complex (MHC) molecules may limit opportunities of B cell to receive CD4+… read more here.
Keywords: nicotine; synthetic nicotine; inkt; nicotine vaccine ... See more keywords
In-silico design of envelope based multi-epitope vaccine candidate against Kyasanur forest disease virus
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-94488-8
Abstract: Kyasanur forest disease virus (KFDV) causing tick-borne hemorrhagic fever which was earlier endemic to western Ghats, southern India, it is now encroaching into new geographic regions, but there is no approved medicine or effective vaccine… read more here.
Keywords: kyasanur forest; vaccine candidates; vaccine; virus ... See more keywords
Vaccine candidates against leishmania under current research
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2018.1459191
Abstract: ABSTRACT Introduction: The search for vaccines to prevent human leishmaniasis is an active field of investigation aimed to prevent the devastating effects of this family of diseases on human health. The design and commercialization of… read more here.
Keywords: candidates leishmania; research; leishmaniasis; leishmania current ... See more keywords