Peptide‐Based Cancer Vaccine Delivery via the STINGΔTM‐cGAMP Complex
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200905
Abstract: With the advent of bioinformatic tools in efficiently predicting neo‐antigens, peptide vaccines have gained tremendous attention in cancer immunotherapy. However, the delivery of peptide vaccines remains a major challenge, primarily due to ineffective transport to… read more here.
Keywords: peptide; cgamp; vaccine delivery; delivery ... See more keywords
Biodegradable Microrobots for DNA Vaccine Delivery.
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DOI: 10.1002/adhm.202202921
Abstract: The delivery of nucleic acid vaccine to stimulate host immune responses against COVID-19 shows promise. However, nucleic acid vaccines have drawbacks, including rapid clearance and poor cellular uptake, that limit their therapeutic potential. Microrobots can… read more here.
Keywords: biodegradable microrobots; dna vaccine; microrobots dna; vaccine delivery ... See more keywords
Engineering the Deformability of Albumin-Stabilized Emulsions for Lymph-Node Vaccine Delivery.
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DOI: 10.1002/adma.202100106
Abstract: A major challenge in vaccine delivery is to achieve robust lymph-node (LN) accumulation, which can capitalize on concentrated immunocytes and cytokines in LNs to stimulate the onset and persistence of adaptive immune responses. Previous attempts… read more here.
Keywords: vaccine delivery; delivery; deformability albumin; deformability ... See more keywords
Efficient Mucosal Immunization by Mucoadhesive and pH-Sensitive Polymeric Vaccine Delivery System
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DOI: 10.1007/s13233-019-7042-3
Abstract: Mucosal surfaces as the largest immune organ of human body cover 400 m2 of the body including the gastrointestinal, urogenital, and respiratory tracts. The local mucosal immunity is an important first line of defense against… read more here.
Keywords: sensitive polymeric; vaccine delivery; mucosal; mucoadhesive sensitive ... See more keywords
Mucosal Vaccine Delivery Using Mucoadhesive Polymer Particulate Systems
Sign Up to like & getrecommendations! Published in 2021 at "Tissue Engineering and Regenerative Medicine"
DOI: 10.1007/s13770-021-00373-w
Abstract: Vaccination has been recently attracted as one of the most successful medical treatments of the prevalence of many infectious diseases. Mucosal vaccination has been interested in many researchers because mucosal immune responses play part in… read more here.
Keywords: polymeric particles; vaccine delivery; delivery; mucosal vaccine ... See more keywords
Administration Routes of Polyethylenimine-Coated PLGA Nanoparticles Encapsulating Angelica Sinensis Polysaccharide Vaccine Delivery System Affect Immune Responses.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00090
Abstract: Nanoparticle vaccine delivery systems have been emerging strategies for inducing potent immune responses to prevent and treat infectious diseases and cancers. The properties of nanoparticle vaccine delivery systems, such as nanoparticle size, surface charge, and… read more here.
Keywords: administration routes; delivery; immune responses; vaccine delivery ... See more keywords
Lipid Nanoparticles-From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement.
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DOI: 10.1021/acsnano.1c04996
Abstract: Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of the COVID-19 mRNA vaccines, LNPs play a key role… read more here.
Keywords: research; vaccine delivery; delivery; nanoparticles liposomes ... See more keywords
Mapping vaccination coverage to explore the effects of delivery mechanisms and inform vaccination strategies
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DOI: 10.1038/s41467-019-09611-1
Abstract: The success of vaccination programs depends largely on the mechanisms used in vaccine delivery. National immunization programs offer childhood vaccines through fixed and outreach services within the health system and often, additional supplementary immunization activities… read more here.
Keywords: vaccination; coverage; immunization; vaccine delivery ... See more keywords
Nanomaterials in tuberculosis DNA vaccine delivery: historical perspective and current landscape
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DOI: 10.1080/10717544.2022.2120565
Abstract: Abstract Vaccinations, especially DNA vaccines that promote host immunity, are the most effective interventions for tuberculosis (TB) control. However, the vaccine delivery system exhibits a significant impact on the protective effects of the vaccine. Recently,… read more here.
Keywords: dna vaccines; delivery systems; nanomaterial based; vaccine delivery ... See more keywords
Inhaled vaccine delivery in the combat against respiratory viruses: a 2021 overview of recent developments and implications for COVID-19.
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DOI: 10.1080/14760584.2021.1903878
Abstract: Introduction: As underlined by the late 2019 outbreak of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), vaccination remains the cornerstone of global health-care. Although vaccines for SARS-CoV-2 are being developed at a record-breaking pace, the majority of… read more here.
Keywords: vaccine delivery; delivery combat; inhaled vaccine; sars cov ... See more keywords
Microneedle technology for potential SARS-CoV-2 vaccine delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Expert opinion on drug delivery"
DOI: 10.1080/17425247.2023.2209718
Abstract: INTRODUCTION Microneedle fabrication was conceptualised in the 1970s as devices for painless transdermal drug delivery. The last two decades have seen considerable research and financial investment in this area with SARS-CoV-2 and other vaccines catalysing… read more here.
Keywords: delivery microneedle; vaccine delivery; delivery; sars cov ... See more keywords