Site‐Specific Multi‐Functionalization of the Carrier Protein CRM197 by Disulfide Rebridging for Conjugate Vaccine Development
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202200408
Abstract: Conjugation of an antigen to a carrier protein is widely used for vaccine development. To develop the next generation of conjugate vaccines, we describe here a method for the controlled multi‐functionalization of the widely employed… read more here.
Keywords: carrier; functionalization; vaccine development; carrier protein ... See more keywords
Successes and Opportunities during the Pandemic: Reflections and Revelations from a Vaccine Development Perspective.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2889
Abstract: The Centre of Regulatory Excellence (CoRE) launched an annual lecture series in 2021 in Singapore to honor the memory of the late Professor Sir Alasdair Breckenridge, CoRE's founding Chair, and foster dialogue on global biomedical… read more here.
Keywords: pandemic reflections; reflections revelations; successes opportunities; vaccine development ... See more keywords
Current approaches to HIV vaccine development: a narrative review
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25793
Abstract: The development of an effective vaccine to protect against HIV is a longstanding global health need complicated by challenges inherent to HIV biology and to the execution of vaccine efficacy testing in the context of… read more here.
Keywords: vaccine development; vaccine; approaches hiv; hiv vaccine ... See more keywords
Immunity and Vaccine Development Against Helicobacter pylori.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2019_370
Abstract: Helicobacter pylori is a highly-adapted gastrointestinal pathogen of humans and the immunology of this chronic infection is extremely complex. Despite the availability of antibiotic therapy, the global incidence of H. pylori infection remains high, particularly… read more here.
Keywords: immunity vaccine; vaccine; helicobacter pylori; development ... See more keywords
Inflammation, Immunity, and Vaccine Development for the Gastric Pathogen Helicobacter pylori.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in microbiology and immunology"
DOI: 10.1007/978-3-030-15138-6_1
Abstract: It has been over 30 years since a link was established between H. pylori infection of the gastric mucosa and the development of chronic gastric diseases. Research in rodent models supported by data from human tissue… read more here.
Keywords: immunity vaccine; infection; inflammation immunity; development ... See more keywords
Coronavirus Disease (COVID-19): Current Status and Prospects for Drug and Vaccine Development
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Medical Research"
DOI: 10.1016/j.arcmed.2020.09.010
Abstract: The Coronavirus disease 2019 (COVID-19) pandemic has spread to almost all nooks and corners of the world. There are numerous potential approaches to pharmacologically fight COVID-19: small-molecule drugs, interferon therapies, vaccines, oligonucleotides, peptides, and monoclonal… read more here.
Keywords: vaccine; coronavirus disease; vaccine development;
COVID-19 vaccine: A recent update in pipeline vaccines, their design and development strategies
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2020.173751
Abstract: Coronavirus Disease 2019 named as COVID-19 imposing a huge burden on public health as well as global economies, is caused by a new strain of betacoronavirus named as SARS-CoV-2. The high transmission rate of the… read more here.
Keywords: covid vaccine; sars cov; vaccine; virus ... See more keywords
The repeated setbacks of HIV vaccine development laid the groundwork for SARS-CoV-2 vaccines
Sign Up to like & getrecommendations! Published in 2022 at "Health Policy and Technology"
DOI: 10.1016/j.hlpt.2022.100619
Abstract: The decades-long effort to produce a workable HIV vaccine has hardly been a waste of public and private resources. To the contrary, the scientific know-how acquired along the way has served as the critical foundation… read more here.
Keywords: hiv vaccine; sars cov; cov vaccines; vaccine ... See more keywords
SARS-CoV-2: Insights into its structural intricacies and functional aspects for drug and vaccine development
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Biological Macromolecules"
DOI: 10.1016/j.ijbiomac.2021.02.212
Abstract: Globally, SARS-CoV-2 has emerged as threat to life and economy. Researchers are trying to find a cure against this pathogen but without much success. Several attempts have been made to understand the atomic level details… read more here.
Keywords: sars cov; drug vaccine; vaccine development;
IgG opsonization of merozoites: multiple immune mechanisms for malaria vaccine development.
Sign Up to like & getrecommendations! Published in 2017 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2017.05.004
Abstract: Global eradication of the human-infecting malaria parasite Plasmodium falciparum, the major cause of malaria mortality, is unlikely to be achieved without an effective vaccine. However, our limited understanding of how protective immune responses target malaria… read more here.
Keywords: vaccine development; igg opsonization; opsonization merozoites; vaccine ... See more keywords
A review of combination adjuvants for malaria vaccines: a promising approach for vaccine development.
Sign Up to like & getrecommendations! Published in 2021 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2021.01.006
Abstract: It is obvious that there is a critical need for an efficient malaria vaccine to accelerate malaria eradication. Currently, recombinant subunit vaccination against malaria using proteins and peptides is gaining attention. However, one of the… read more here.
Keywords: malaria vaccines; review; combination adjuvants; vaccine ... See more keywords