Exosomes: Biogenesis, targeting, characterization and their potential as "Plug & Play" vaccine platforms
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Journal"
DOI: 10.1002/biot.202100646
Abstract: Exosomes are typically characterized as spherical extracellular vesicles less than 150 nm in diameter that have been released into the extracellular environment via fusion of multivesicular bodies (MVBs) to the plasma membrane. Exosomes play a… read more here.
Keywords: cell; exosomes biogenesis; vaccine platforms; potential ... See more keywords
Vaccine platforms for the prevention of Lassa fever
Sign Up to like & getrecommendations! Published in 2019 at "Immunology Letters"
DOI: 10.1016/j.imlet.2019.03.008
Abstract: Abstract Lassa fever is an acute viral haemorrhagic illness caused by Lassa virus (LASV), which is endemic throughout much of West Africa. The virus primarily circulates in the Mastomys natalensis reservoir and is transmitted to… read more here.
Keywords: fever vaccine; platforms prevention; fever; vaccine platforms ... See more keywords
Comparative study of α-helical and β-sheet self-assembled peptide nanofiber vaccine platforms: influence of integrated T-cell epitopes.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials science"
DOI: 10.1039/d0bm00521e
Abstract: Several different self-assembling peptide systems that form nanofibers have been investigated as vaccine platforms, but design principles for adjusting the character of the immune responses they raise have yet to be well articulated. Here we… read more here.
Keywords: integrated cell; cell epitopes; coil29 nanofibers; self assembled ... See more keywords
Diverse vaccine platforms safeguarding against SARS-CoV-2 and its variants.
Sign Up to like & getrecommendations! Published in 2021 at "Expert review of vaccines"
DOI: 10.1080/14760584.2022.1997601
Abstract: INTRODUCTION Appearances of SARS-CoV-2 variants have created havoc and additional challenges for the ongoing vaccination drive against pandemic COVID-19. Interestingly, several vaccine platforms are showing great potential to produce successful vaccines against SARS-CoV-2 and its… read more here.
Keywords: covid vaccines; diverse vaccine; cov variants; sars cov ... See more keywords
Recent Updates on COVID-19 Vaccine Platforms and Its Immunological Aspects: A Review
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DOI: 10.31838/srp.2020.10.121
Abstract: SARS-CoV-2 firstly emerged in China and sporadically transmitted worldwide. In March 2020, WHO announced that the infection was a pandemic. The outbreak and rapid transmission of COVID-19 have endangered the global health and the economy.… read more here.
Keywords: covid vaccine; updates covid; sars cov; recent updates ... See more keywords
Current Vaccine Platforms in Enhancing T-Cell Response
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DOI: 10.3390/vaccines10081367
Abstract: The induction of T cell-mediated immunity is crucial in vaccine development. The most effective vaccine is likely to employ both cellular and humoral immune responses. The efficacy of a vaccine depends on T cells activated… read more here.
Keywords: cell; vaccine platforms; platforms enhancing; immunity ... See more keywords