Exploring evidence for behavioral risk compensation among participants in an HIV vaccine clinical trial.
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DOI: 10.1016/j.vaccine.2017.05.024
Abstract: BACKGROUND HIV vaccine trial participants may engage in behavioral risk compensation due to a false sense of protection. We conducted an ancillary study of an HIV Vaccine Trials Network (HVTN) vaccine efficacy trial to explore… read more here.
Keywords: trial participants; trial; vaccine trial; risk compensation ... See more keywords
Expected endpoints from future chikungunya vaccine trial sites informed by serological data and modeling
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DOI: 10.1101/2022.05.23.22275466
Abstract: In recent decades, there has been an increased interest in developing a vaccine for chikungunya. However, due to its unpredictable transmission, planning for a chikungunya vaccine trial is challenging. To inform decision making on the… read more here.
Keywords: trial; chikungunya vaccine; vaccine trial; endpoint events ... See more keywords
Vaccine trial launched to stop Ebola.
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DOI: 10.1126/science.360.6390.694
Abstract: On 8 May, the Democratic Republic of the Congo (DRC) announced that a new Ebola outbreak was underway in a remote part of the country, and within 3 days, the government decided for the first… read more here.
Keywords: launched stop; trial; vaccine trial; trial launched ... See more keywords
Choices in vaccine trial design in epidemics of emerging infections
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DOI: 10.1371/journal.pmed.1002632
Abstract: In a Policy Forum, Marc Lipsitch and colleagues discuss trial design issues in infectious disease outbreaks. read more here.
Keywords: trial; vaccine trial; design epidemics; trial design ... See more keywords
A Quantitative Approach to Unravel the Role of Host Genetics in IgG-FcγR Complex Formation After Vaccination
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DOI: 10.3389/fimmu.2022.820148
Abstract: Fc-mediated immune functions have been correlated with protection in the RV144 HIV vaccine trial and are important for immunity to a range of pathogens. IgG antibodies (Abs) that form complexes with Fc receptors (FcRs) on… read more here.
Keywords: complex formation; vaccination; vaccine trial; vaccine ... See more keywords
Willingness to Participate and Associated Factors in a Zika Vaccine Trial in Indonesia: A Cross-Sectional Study
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DOI: 10.3390/v10110648
Abstract: One of the crucial steps during trials for Zika and other vaccines is to recruit participants and to understand how participants’ attitudes and sociodemographic characteristics affect willingness to participate (WTP). This study was conducted to… read more here.
Keywords: cross sectional; willingness participate; vaccine trial; study ... See more keywords
The Impact of Educational Intervention on Willingness to Enroll in a Clinical Trial of a Gonorrhea Vaccine
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DOI: 10.3390/vaccines11030648
Abstract: Globally, >80 million new gonorrhea infections occur annually. Here, we assessed barriers to and influences on participation in a gonorrhea clinical trial and the impact of educational intervention. The survey was fielded in the US… read more here.
Keywords: educational intervention; gonorrhea vaccine; trial; vaccine trial ... See more keywords