Vaccine vectors: the bright side of cytomegalovirus
Sign Up to like & getrecommendations! Published in 2019 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-019-00597-7
Abstract: Cytomegaloviruses (CMVs) present singular features that are particularly advantageous for human vaccine development, a current medical need. Vaccines that induce neutralizing antibodies are among the most successful and efficacious available. However, chronic and persistent human… read more here.
Keywords: bright side; cmv; side cytomegalovirus; vectors bright ... See more keywords
MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-021-00814-5
Abstract: Global pandemics caused by influenza or coronaviruses cause severe disruptions to public health and lead to high morbidity and mortality. There remains a medical need for vaccines against these pathogens. CMV (cytomegalovirus) is a β-herpesvirus… read more here.
Keywords: mcmv; immune; protection; vaccine vectors ... See more keywords
New gorilla adenovirus vaccine vectors induce potent immune responses and protection in a mouse malaria model
Sign Up to like & getrecommendations! Published in 2017 at "Malaria Journal"
DOI: 10.1186/s12936-017-1911-z
Abstract: BackgroundA DNA-human Ad5 (HuAd5) prime-boost malaria vaccine has been shown to protect volunteers against a controlled human malaria infection. The potency of this vaccine, however, appeared to be affected by the presence of pre-existing immunity… read more here.
Keywords: pycsp; gorilla; malaria vaccine; vaccine vectors ... See more keywords
Vaccine Vectors Harnessing the Power of Cytomegaloviruses
Sign Up to like & getrecommendations! Published in 2019 at "Vaccines"
DOI: 10.3390/vaccines7040152
Abstract: Cytomegalovirus (CMV) species have been gaining attention as experimental vaccine vectors inducing cellular immune responses of unparalleled strength and protection. This review outline the strengths and the restrictions of CMV-based vectors, in light of the… read more here.
Keywords: vectors harnessing; harnessing power; cmv based; power cytomegaloviruses ... See more keywords