KRAS Inhibitors- yes but what next? Direct targeting of KRAS- vaccines, adoptive T cell therapy and beyond.
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DOI: 10.1016/j.ctrv.2021.102309
Abstract: Kirsten rat sarcoma viral oncogene homolog (KRAS) is a proto-oncogene of the RAS-MAPK pathway. KRAS mutations are present in a variety of malignancies including lung, colorectal, and pancreatic cancer. Until the recent approval of sotorasib,… read more here.
Keywords: kras inhibitors; cell therapy; adoptive cell; vaccines adoptive ... See more keywords