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Published in 2021 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2229
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) causes an acute infection that is controlled by the immune response. The virus has a dominant surface protein that is highly immunogenic and it can be presumed that…
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Keywords:
vaccinology;
adenovirus;
sars cov;
new normal ... See more keywords
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Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.07.062
Abstract: Abstract At the current time, the field of vaccinology remains empirical in many respects. Vaccine development, vaccine immunogenicity, and vaccine efficacy have, for the most part, historically been driven by an empiric “isolate-inactivate-inject” paradigm. In…
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Keywords:
medicine;
vaccinology review;
vaccinology;
vaccine ... See more keywords
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Published in 2022 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2022.2093193
Abstract: ABSTRACT Introduction Vaccines have had a transformative impact on child health. Despite this impact, the immunological processes involved in protective responses are not entirely understood and vaccine development has been largely empirical. Recent technological advances…
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Keywords:
omics strategy;
vaccinology;
systems vaccinology;
childhood immunization ... See more keywords
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Published in 2018 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2018.1413088
Abstract: ABSTRACT Introduction: Vaccinology has evolved from a sub-discipline focussed on simplistic vaccine development based on antibody-mediated protection to a separate discipline involving epidemiology, host and pathogen biology, immunology, genomics, proteomics, structure biology, protein engineering, chemical…
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Keywords:
data mining;
vaccinology;
biology;
vaccine ... See more keywords
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Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac190
Abstract: Rational vaccine design, especially vaccine antigen identification and optimization, is critical to successful and efficient vaccine development against various infectious diseases including coronavirus disease 2019 (COVID-19). In general, computational vaccine design includes three major stages:…
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Keywords:
vaccine design;
machine learning;
ontology;
vaccinology ... See more keywords
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Published in 2019 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2019.00107
Abstract: Objectives: Novel approaches to advance the field of vaccinology must be investigated, and are particularly of importance for influenza in order to produce a more effective vaccine. A systematic review of human challenge studies for…
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Keywords:
human challenge;
influenza;
vaccinology;
biology ... See more keywords
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Published in 2021 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"
DOI: 10.3760/cma.j.cn112150-20210616-00592
Abstract: Although there has been over 200 years in history for vaccination practice and its value has been fully confirmed, the health care providers in China have far less knowledge of vaccines than clinical drugs. The…
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Keywords:
vaccinology education;
vaccinology;
health;
medical professionals ... See more keywords