LAMTOR1 ubiquitination restricts its interaction with the vacuolar-type H+-ATPase, promotes autophagy and is controlled by USP32.
Sign Up to like & getrecommendations! Published in 2023 at "Autophagy"
DOI: 10.1080/15548627.2023.2184958
Abstract: Among the various signals governing autophagy, ubiquitination plays a critical role both by controlling the stability of upstream regulators or components of macroautophagy/autophagy pathways and by facilitating the recruitment of cargo to autophagy receptors. As… read more here.
Keywords: vacuolar type; type atpase; lamtor1 ubiquitination; interaction vacuolar ... See more keywords
Acidification of endothelial Weibel-Palade bodies is mediated by the vacuolar-type H+-ATPase
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0270299
Abstract: Weibel-Palade bodies (WPB) are unique secretory granules of endothelial cells that store the procoagulant von-Willebrand factor (VWF) in a highly compacted form. Upon exocytosis the densely packed VWF unfurls into long strands that expose binding… read more here.
Keywords: vacuolar type; type atpase; wpb; acidification ... See more keywords