Vagus Nerves Provide a Robust Afferent Innervation of the Mucosa Throughout the Body of the Esophagus in the Mouse
Sign Up to like & getrecommendations! Published in 2019 at "Dysphagia"
DOI: 10.1007/s00455-019-10051-8
Abstract: The vagal afferent nerves regulate swallowing and esophageal motor reflexes. However, there are still gaps in the understanding of vagal afferent innervation of the esophageal mucosa. Anatomical studies found that the vagal afferent mucosal innervation… read more here.
Keywords: body esophagus; vagal afferent; afferent innervation; afferent ... See more keywords
Gastric vagal afferent neuropathy following experimental spinal cord injury
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2019.113092
Abstract: Dramatic impairment of gastrointestinal (GI) function accompanies high-thoracic spinal cord injury (T3-SCI). The vagus nerve contains mechano- and chemosensory fibers as well as the motor fibers necessary for the central nervous system (CNS) control of… read more here.
Keywords: sci; vagal afferent; response; afferent ... See more keywords
Mechanisms of reduced leptin-mediated satiety signaling during obesity
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Obesity"
DOI: 10.1038/s41366-022-01079-2
Abstract: Disrupted leptin signaling in vagal afferent neurons contributes to hyperphagia and obesity. Thus, we tested the hypothesis that intrinsic negative regulators of leptin signaling, suppressor of cytokine signaling 3 (SOCS3) and protein tyrosine phosphatase 1B… read more here.
Keywords: leptin mediated; satiety; obesity; vagal afferent ... See more keywords
Functional interaction between Ghrelin and GLP-1 regulates feeding through the vagal afferent system
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-75621-5
Abstract: The gastrointestinal tract transmits feeding-regulatory signals to the brain via neuronal and hormonal pathways. Here we studied the interaction between the orexigenic gastric peptide, ghrelin, and the anorectic intestinal peptide, glucagon-like peptide 1 (GLP-1), in… read more here.
Keywords: vagal afferent; glp; preadministration; interaction ... See more keywords
Vagal Afferent Innervation of the Atria and Ventricles of the Rat Heart: Anterograde Tracing
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733692
Abstract: Vagal afferent innervation of the atria from the nodose ganglion has been shown in previous studies but the innervation of the ventricles remains unknown. In this study, tracer Dextran-Biotin was injected into the left nodose… read more here.
Keywords: atria ventricles; afferent innervation; physiology; heart ... See more keywords
Curcumin Activates Vagal Afferent Neurons Through the Modulation of Ion Channels via α7 nAChR
Sign Up to like & getrecommendations! Published in 2019 at "Natural Product Communications"
DOI: 10.1177/1934578x19873738
Abstract: Curcumin, a plant polyphenol, has been previously reported to attenuate collagen-induced arthritis in rats by modulating the function of the cholinergic system, but the underlying mechanism remains to be identified. In this study, primary nodose… read more here.
Keywords: afferent neurons; activates vagal; curcumin; neurons modulation ... See more keywords
Expression of proteinase-activated receptor-2 and transient receptor potential A1 in vagal afferent nerve of rat after lung schemia-reperfusion injury.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/18-207-a
Abstract: Lung ischemia-reperfusion injury (LIRI) is a common and severe clinical complication. As the injury occurs, the pulmonary afferent nerves play an important role in regulating respiratory functions under pathophysiological conditions. The purpose of this study… read more here.
Keywords: afferent nerves; par2 trpa1; receptor; vagal afferent ... See more keywords
Colonic Motility and Jejunal Vagal Afferent Firing Rates Are Decreased in Aged Adult Male Mice and Can Be Restored by an Aminosterol
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.00955
Abstract: There is a general decline in gastrointestinal function in old age including decreased intestinal motility, sensory signaling, and afferent sensitivity. There is also increased prevalence of significant constipation in aged populations. We hypothesized this may… read more here.
Keywords: vagal afferent; mice; afferent firing; colonic motility ... See more keywords
Cultured Vagal Afferent Neurons as Sensors for Intestinal Effector Molecules
Sign Up to like & getrecommendations! Published in 2023 at "Biosensors"
DOI: 10.3390/bios13060601
Abstract: The gut–brain axis embodies the bi-directional communication between the gastrointestinal tract and the central nervous system (CNS), where vagal afferent neurons (VANs) serve as sensors for a variety of gut-derived signals. The gut is colonized… read more here.
Keywords: effector; neurons sensors; afferent neurons; cultured vagal ... See more keywords
Endocannabinoids and the Gut-Brain Control of Food Intake and Obesity
Sign Up to like & getrecommendations! Published in 2021 at "Nutrients"
DOI: 10.3390/nu13041214
Abstract: Gut-brain signaling controls food intake and energy homeostasis, and its activity is thought to be dysregulated in obesity. We will explore new studies that suggest the endocannabinoid (eCB) system in the upper gastrointestinal tract plays… read more here.
Keywords: vagal afferent; food intake; obesity; brain ... See more keywords