Mrgprs on vagal sensory neurons contribute to bronchoconstriction and airway hyperresponsiveness
Sign Up to like & getrecommendations! Published in 2018 at "Nature neuroscience"
DOI: 10.1038/s41593-018-0074-8
Abstract: Asthma, accompanied by lung inflammation, bronchoconstriction and airway hyper-responsiveness, is a significant public health burden. Here we report that Mas-related G protein-coupled receptors (Mrgprs) are expressed in a subset of vagal sensory neurons innervating the… read more here.
Keywords: mrgprs vagal; neurons contribute; bronchoconstriction airway; bronchoconstriction ... See more keywords
PANCREATIC BETA CELLS COMMUNICATE WITH VAGAL SENSORY NEURONS.
Sign Up to like & getrecommendations! Published in 2020 at "Gastroenterology"
DOI: 10.1053/j.gastro.2020.10.034
Abstract: BACKGROUND AND AIMS Destroying visceral sensory nerves impacts pancreatic islet function, glucose metabolism and diabetes onset, but how islet endocrine cells interact with sensory neurons has not been studied. METHODS We characterized the anatomical pattern… read more here.
Keywords: beta cells; serotonin; beta; pancreatic beta ... See more keywords
Ontogeny and Trophic Factor Sensitivity of Gastrointestinal Projecting Vagal Sensory Cell Types
Sign Up to like & getrecommendations! Published in 2022 at "eNeuro"
DOI: 10.1523/eneuro.0511-22.2023
Abstract: Abstract Vagal sensory neurons (VSNs) located in the nodose ganglion provide information, such as stomach stretch or the presence of ingested nutrients, to the caudal medulla via specialized cell types expressing unique marker genes. Here,… read more here.
Keywords: cell; cell types; factor; factor sensitivity ... See more keywords
Modulation of Vagal Sensory Neurons via High Mobility Group Box-1 and Receptor for Advanced Glycation End Products: Implications for Respiratory Viral Infections
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.744812
Abstract: Vagal sensory neurons contribute to the symptoms and pathogenesis of inflammatory pulmonary diseases through processes that involve changes to their morphological and functional characteristics. The alarmin high mobility group box-1 (HMGB1) is an early mediator… read more here.
Keywords: hmgb1; high mobility; rage; sensory neurons ... See more keywords