The Role of 17β-Estrogen in Candida albicans Adhesion on Human Vaginal Epithelial Cells via FAK Phosphorylation
Sign Up to like & getrecommendations! Published in 2020 at "Mycopathologia"
DOI: 10.1007/s11046-020-00440-1
Abstract: To investigate the role of 17β-estrogen in Candida albicans (C. albicans) adhesion on human vaginal epithelial cells in vulvovaginal candidiasis (VVC). The vaginal epithelial cell line, VK2/E6E7, was used to study the estrogen-induced molecular events… read more here.
Keywords: role estrogen; epithelial cells; vaginal epithelial; estrogen ... See more keywords
Neisseria gonorrhoeae modifies its infectivity based on the types of human cervical epithelial cells and the expression of its surface molecules: 29
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2017.08.050
Abstract: METHODS: We evaluated the cytotoxic activity of the Baofukang suppository using the VK2/E6E7 vaginal epithelial cell (VEC) line. An ELISA analysis was made to evaluate three kinds of cytokines (Th1, Th2 and Th17 types) and… read more here.
Keywords: baofukang suppository; vaginal epithelial; modifies infectivity; gonorrhoeae modifies ... See more keywords
Characterization of Gardnerella vaginalis membrane vesicles reveals a role in inducing cytotoxicity in vaginal epithelial cells.
Sign Up to like & getrecommendations! Published in 2019 at "Anaerobe"
DOI: 10.1016/j.anaerobe.2019.102090
Abstract: Bacterial vaginosis (BV) is a common polymicrobial infection affecting women in the reproductive age and is associated with adverse obstetric and gynaecological outcomes. Gardnerella vaginalis is the most virulent anaerobic bacterial species predominantly associated with… read more here.
Keywords: epithelial cells; vaginal epithelial; gardnerella vaginalis; membrane vesicles ... See more keywords
Cell Lineage Tracing Identifies Hormone-Regulated and Wnt-Responsive Vaginal Epithelial Stem Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.01.003
Abstract: The intact vaginal epithelium is essential for women's reproductive health and provides protection against HIV and sexually transmitted infections. How this epithelium maintains itself remains poorly understood. Here, we used single-cell RNA sequencing (RNA-seq) to… read more here.
Keywords: vaginal epithelium; vaginal epithelial; epithelial stem; stem ... See more keywords
The composition of the vaginal microbiome in first trimester pregnant women influences the level of autophagy and stress in vaginal epithelial cells.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2017.08.009
Abstract: Epithelial cells lining the vagina are major components of genital tract immunity. The influence of the vaginal microbiome on properties of host epithelial cells is largely unexplored. We evaluated whether differences in the most abundant… read more here.
Keywords: epithelial cells; vaginal epithelial; pregnant women; vaginal microbiome ... See more keywords
Adenosine, but not guanosine, protects vaginal epithelial cells from Trichomonas vaginalis cytotoxicity.
Sign Up to like & getrecommendations! Published in 2017 at "Microbes and infection"
DOI: 10.1016/j.micinf.2016.11.001
Abstract: Trichomonas vaginalis causes the most common non-viral sexually transmitted disease worldwide. The cytoadherence and cytotoxicity upon the vaginal epithelial cells are crucial for the infection. Extracellular nucleotides are released during cell damage and, along with… read more here.
Keywords: epithelial cells; vaginalis cytotoxicity; vaginal epithelial; guanosine ... See more keywords
Pathogen Stimulation of Interleukin-8 from Human Vaginal Epithelial Cells through CD40
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00106-22
Abstract: Most bacterial and fungal pathogens cause disease across mucosal, and to a lesser extent, skin barriers with the help of induced chemokines from epithelial cells. In this study, we showed that potential vaginal pathogens Staphylococcus… read more here.
Keywords: cause disease; cd40; epithelial cells; vaginal epithelial ... See more keywords
Group B streptococcus exploits vaginal epithelial exfoliation for ascending infection
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Investigation"
DOI: 10.1172/jci97043
Abstract: Thirteen percent of pregnancies result in preterm birth or stillbirth, accounting for fifteen million preterm births and three and a half million deaths annually. A significant cause of these adverse pregnancy outcomes is in utero… read more here.
Keywords: vaginal epithelial; ascending infection; group streptococcus; infection ... See more keywords
Polyethylene glycol-functionalized poly (Lactic Acid-co-Glycolic Acid) and graphene oxide nanoparticles induce pro-inflammatory and apoptotic responses in Candida albicans-infected vaginal epithelial cells
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DOI: 10.1371/journal.pone.0175250
Abstract: Mucous-penetrating nanoparticles consisting of poly lactic acid-co-glycolic acid (PLGA)-polyethylene glycol (PEG) could improve targeting of microbicidal drugs for sexually transmitted diseases by intravaginal inoculation. Nanoparticles can induce inflammatory responses, which may exacerbate the inflammation that… read more here.
Keywords: poly lactic; vaginal epithelial; expression; peg ... See more keywords
Recombinant Human IFNα-2b Response Promotes Vaginal Epithelial Cells Defense against Candida albicans
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DOI: 10.3389/fmicb.2017.00697
Abstract: Classical antifungal drugs have been subjected to restrictions due to drug toxicity, drug resistance, bioavailability, and detrimental drug interactions. Type I interferon (IFN) exerts direct distinct immunostimulatory or immunomodulatory actions; however, little is known regarding… read more here.
Keywords: recombinant human; epithelial cells; response; vaginal epithelial ... See more keywords
Berberine Inhibits the Adhesion of Candida albicans to Vaginal Epithelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.814883
Abstract: Vulvovaginal candidiasis (VVC) is an inflammatory disease of the vagina mainly caused by Candida albicans (C. albicans), which affects around three-quarters of all women during their reproductive age. Although some antifungal drugs such as azoles… read more here.
Keywords: adhesion albicans; albicans vaginal; epithelial cells; vaginal epithelial ... See more keywords