Evaluation Methods for Mechanical Biocompatibility of Innovative Prolapse Repair Meshes
Sign Up to like & getrecommendations! Published in 2025 at "International Journal for Numerical Methods in Biomedical Engineering"
DOI: 10.1002/cnm.70115
Abstract: Pelvic organ prolapse (POP) affects many women and involves the displacement of pelvic organs due to weakened support structures. While synthetic meshes are used in surgeries to reinforce these structures, they can lead to complications… read more here.
Keywords: prolapse; simulation; mesh implants; vaginal tissue ... See more keywords
A physiologically relevant, estradiol‐17β [E2]‐responsive in vitro tissue‐engineered model of the vaginal epithelium for vaginal tissue research
Sign Up to like & getrecommendations! Published in 2022 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.24908
Abstract: There are many situations where preclinical models of the human vagina would be valuable for in vitro studies into the pathophysiology of vaginally transmitted diseases, microbicide efficacy, irritability testing, and particularly, for assessing materials to… read more here.
Keywords: relevant estradiol; model; physiologically relevant; vaginal tissue ... See more keywords
Inflation and rupture of vaginal tissue
Sign Up to like & getrecommendations! Published in 2019 at "Interface Focus"
DOI: 10.1098/rsfs.2019.0029
Abstract: Around 80% of women experience vaginal tears during labour when the diameter of the vagina must increase to allow the passage of a full-term baby. Current techniques for evaluating vaginal tears are qualitative and often… read more here.
Keywords: direction; rupture vaginal; tissue; vaginal tissue ... See more keywords
Contractile Properties of Vaginal Tissue.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4046712
Abstract: The vagina is an important organ of the female reproductive system that has been largely under- studied in the field of biomechanics. In recent years, some research has been conducted to evaluate the mechanical properties… read more here.
Keywords: properties vaginal; research; biomechanics; properties vagina ... See more keywords
Biodegradable mesh implants for prolapse repair: Advances in computational modelling and experimental validation
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine"
DOI: 10.1177/09544119251323336
Abstract: Pelvic organ prolapse (POP) limits people’s quality of life and is quite common in women, especially with advancing age. As cases increase, there is an urgent need for alternative treatments, especially for severe POP, where… read more here.
Keywords: pop; biodegradable mesh; repair; mesh implants ... See more keywords
Safety and efficacy of G2-S16 dendrimer as microbicide in healthy human vaginal tissue explants
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-022-01350-8
Abstract: Background The absence of an effective treatment and vaccine in HIV-1 pandemic place preventive strategies such as safety and effective microbicide development as a central therapeutic approach to control HIV-1 pandemic nowadays. Results Studies of… read more here.
Keywords: microbicide; vaginal tissue; s16 dendrimer; tissue explants ... See more keywords