Metastable Iron Sulfides Gram‐Dependently Counteract Resistant Gardnerella Vaginalis for Bacterial Vaginosis Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202104341
Abstract: Bacterial vaginosis (BV) is the most common vaginal infection found in women in the world. Due to increasing drug‐resistance of virulent pathogen such as Gardnerella vaginalis (G. vaginalis), more than half of BV patients suffer… read more here.
Keywords: gardnerella vaginalis; iron; metastable iron; bacterial vaginosis ... See more keywords
Epinecidin-1: A marine fish antimicrobial peptide with therapeutic potential against Trichomonas vaginalis infection in mice
Sign Up to like & getrecommendations! Published in 2019 at "Peptides"
DOI: 10.1016/j.peptides.2018.12.004
Abstract: HIGHLIGHTSThe synthetic fish Epinecidin‐1 (Epi‐1), acts against T. vaginalis both in vitro and in vivo.After one week, the T. vaginalis content was effectively decreased in Epi‐1 treated mice.Epi‐1 is a strong candidate for development as… read more here.
Keywords: infection; mice; trichomonas vaginalis; vaginalis ... See more keywords
Anti-Trichomonas vaginalis activity of 1,10-phenanthroline-5,6-dione-based metallodrugs and synergistic effect with metronidazole
Sign Up to like & getrecommendations! Published in 2018 at "Parasitology"
DOI: 10.1017/s003118201800152x
Abstract: Abstract Trichomonas vaginalis is responsible for the most common non-viral, sexually transmitted infection, human trichomoniasis, and is associated with an increased susceptibility to HIV. An escalation in resistance (2.5–10%) to the clinical drug, metronidazole (MTZ),… read more here.
Keywords: phendione clo4; vaginalis; trichomonas vaginalis; phendione ... See more keywords
Chemotactic behaviour of Giardia lamblia and Trichomonas vaginalis towards nutrient sources
Sign Up to like & getrecommendations! Published in 2025 at "Parasitology"
DOI: 10.1017/s0031182025000484
Abstract: Chemotaxis is the phenomenon of sensing external concentration gradients by cells and the cellular movement towards or away from the cells. While there have been intensive studies on prokaryotes, little research has been conducted on… read more here.
Keywords: vaginalis; giardia lamblia; chemotactic behaviour; trichomonas vaginalis ... See more keywords
Expanding the antiprotozoal activity and the mechanism of action of n-butyl and iso-butyl ester of quinoxaline-1,4-di-N-oxide derivatives against Giardia lamblia, Trichomonas vaginalis, and Entamoeba histolytica. An in vitro and in silico approach
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2024.2413018
Abstract: Abstract In this study, n-butyl and iso-butyl quinoxaline-7-carboxylate-1,4-di-N-oxide derivatives were evaluated in vitro against Giardia lamblia (G. lamblia), Trichomonas vaginalis (T. vaginalis), and Entamoeba histolytica (E. histolytica). The potential mechanism of action determination was approached… read more here.
Keywords: butyl iso; vaginalis; butyl; iso butyl ... See more keywords
Comparison of Seegene AnyPlexTM II STI-7e with standard-of-care diagnostic methods for the detection of Mycoplasma genitalium, Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis.
Sign Up to like & getrecommendations! Published in 2023 at "Letters in applied microbiology"
DOI: 10.1093/lambio/ovac002
Abstract: The AnyPlexTM II STI-7e panel assay (Seegene) detects seven sexually transmitted organisms (Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, M. hominis, Ureaplasma urealyticum, U. parvum, and Trichomonas vaginalis). This study compared the performance of AnyPlexTM II… read more here.
Keywords: anyplextm sti; standard care; trachomatis; detection ... See more keywords
Positivity and Risk Factors for Trichomonas vaginalis Among Women Attending a Sexual Health Clinic in Melbourne, 2006 to 2019
Sign Up to like & getrecommendations! Published in 2022 at "Sexually Transmitted Diseases"
DOI: 10.1097/olq.0000000000001690
Abstract: The positivity of Trichomonas vaginalis is rising in female clients in Melbourne, Australia. Associated factors include concurrent syphilis, concurrent chlamydia, injecting drug use in the last 12 months, and age of at least 35 years.… read more here.
Keywords: 2006 2019; positivity; women attending; sexual health ... See more keywords
Updates in trichomonas treatment including persistent infection and 5-nitroimidazole hypersensitivity.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000618
Abstract: PURPOSE OF REVIEW The purpose of this review is to update information on treatment of Trichomonas vaginalis. T. vaginalis is estimated to be the most common treatable sexually transmitted infection. In the world and is… read more here.
Keywords: vaginalis; trichomonas treatment; updates trichomonas; treatment ... See more keywords
Focusing the diversity of Gardnerella vaginalis through the lens of ecotypes
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DOI: 10.1111/eva.12555
Abstract: Gardnerella vaginalis has long been associated with bacterial vaginosis, a condition that increases the risk of women to preterm birth, sexually transmitted infections, and other adverse sequelae. However, G. vaginalis is also commonly found in… read more here.
Keywords: analysis; focusing diversity; gardnerella vaginalis; vaginalis ... See more keywords
Biogenesis of Autophagosome in Trichomonas vaginalis during Macroautophagy Induced by Rapamycin‐treatment and Iron or Glucose Starvation Conditions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Eukaryotic Microbiology"
DOI: 10.1111/jeu.12712
Abstract: Autophagy is an adaptive response for cell survival in which cytoplasmic components and organelles are degraded in bulk under normal and stress conditions. Trichomonas vaginalis is a parasite highly adaptable to stress conditions such as… read more here.
Keywords: starvation; treatment; autophagy; trichomonas vaginalis ... See more keywords
Lacticaseibacillus rhamnosus Lcr35 Stimulates Epithelial Vaginal Defenses upon Gardnerella vaginalis Infection
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Immunity"
DOI: 10.1128/iai.00309-22
Abstract: Dysbiosis of the vaginal microbiome as a result of overgrowth of anaerobic bacteria, such as Gardnerella vaginalis, and low levels of “healthy” lactobacilli leads to bacterial vaginosis (BV), usually associated with a low-grade inflammatory process.… read more here.
Keywords: gardnerella vaginalis; infection; vaginalis infection; vaginalis ... See more keywords