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   Articles with "val" as a keyword



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Synthesis and biological evaluation of Val–Val dipeptide–sulfonamide conjugates

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recommendations! Published in 2020 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.202000074

Abstract: Novel Val–Val dipeptide–benzenesulfonamide conjugates were reported in this study. These were achieved by a condensation reaction of p‐substituted benzenesulfonamoyl alkanamides with 2‐amino‐4‐methyl‐N‐substituted phenyl butanamide using classical peptide‐coupling reagents. The compounds were characterized using Fourier transform… read more here.

Keywords: val dipeptide; biological evaluation; val; synthesis biological ... See more keywords
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Isolation of high-purity peptide Val-Val-Tyr-Pro from Globin Peptide using MCI gel column combined with high-speed counter-current chromatography.

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recommendations! Published in 2018 at "Journal of separation science"

DOI: 10.1002/jssc.201800972

Abstract: Peptides have gained increased interest over the past several decades because of their therapeutics. In this research, a strategy combining MCI gel column chromatography and high-speed countercurrent chromatography was developed for the separation of high-purity… read more here.

Keywords: chromatography; val tyr; val; purity ... See more keywords
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Direct glucosone-based synthesis and HILIC-ESI-MS/MS characterization of N-terminal fructosylated valine and valylhistidine for validation of enzymatic HbA1c assays in the diagnosis of diabetes mellitus

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recommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-019-02186-2

Abstract: Naturally occurring fructosamines are of high clinical significance due to their potential use in diabetes mellitus monitoring (quantification of fructosylated hemoglobin, HbA1c) or for the investigation of their reactivity in consecutive reactions and harmfulness towards… read more here.

Keywords: val; enzymatic hba1c; diabetes mellitus; fru val ... See more keywords
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Effects of Diclofenac Versus Meloxicam in Pentylenetetrazol-Kindled Mice

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recommendations! Published in 2020 at "Neurochemical Research"

DOI: 10.1007/s11064-020-03054-7

Abstract: Epilepsy comes after stroke as the most common chronic neurological disorder worldwide. Inflammation enhances neuronal hyperexcitability that could provide a background setting for the development of epilepsy. The aim of this study was to assess… read more here.

Keywords: kindled mice; val dic; val; val mel ... See more keywords
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MOF Capacitates Cyclodextrin to Mega-Load Mode for High-Efficient Delivery of Valsartan

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recommendations! Published in 2019 at "Pharmaceutical Research"

DOI: 10.1007/s11095-019-2650-3

Abstract: PurposeTo investigate the mechanism of enhancing solubility and bioavailability of water-insoluble drug, valsartan (VAL), with being mega-loaded by cyclodextrin metal organic framework (CD-MOF).MethodsVAL was successfully mega-loaded into CD-MOF by magnetic agitation of VAL in ethanolic solution. Characterizations… read more here.

Keywords: valsartan; mof; val; delivery ... See more keywords
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Associations between PRF1 Ala91Val polymorphism and risk of hemophagocytic lymphohistiocytosis: a meta-analysis based on 1366 subjects

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recommendations! Published in 2020 at "World Journal of Pediatrics"

DOI: 10.1007/s12519-020-00351-7

Abstract: Perforin (PRF1) gene mutation can cause the onset of hemophagocytic lymphohistiocytosis (HLH). It has reported that PRF1 Ala91Val polymorphism was related with HLH risk. In the meta-analysis, we aim to evaluate the association between PRF1… read more here.

Keywords: ala; val; analysis; prf1 ala91val ... See more keywords
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Impact of COMT val158met on tDCS-induced cognitive enhancement in older adults

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recommendations! Published in 2021 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2020.113081

Abstract: BACKGROUND Previous studies suggest that genetic polymorphisms and aging modulate inter-individual variability in brain stimulation-induced plasticity. However, the relationship between genetic polymorphisms and behavioral modulation through transcranial direct current stimulation (tDCS) in older adults remains… read more here.

Keywords: tdcs responsiveness; tdcs; val; brain ... See more keywords
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Application of an LC–MS/MS method for the analysis of amlodipine, valsartan and hydrochlorothiazide in polypill for a bioequivalence study

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recommendations! Published in 2017 at "Journal of Pharmaceutical Analysis"

DOI: 10.1016/j.jpha.2017.06.001

Abstract: A sensitive and selective method has been proposed for the simultaneous determination of amlodipine (AML), valsartan (VAL) and hydrochlorothiazide (HCTZ) in human plasma by liquid chromatography–tandem mass spectrometry (LC–MS/MS). The analytes and their deuterated analogs… read more here.

Keywords: valsartan; val; method; hctz ... See more keywords

Decatungstate-Catalyzed C(sp3)-H Alkylation of a Val Residue Proximal to the N-Terminus Controlled by an Electrostatic Interaction.

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recommendations! Published in 2023 at "Organic letters"

DOI: 10.1021/acs.orglett.3c01154

Abstract: The decatungstate photocatalyst [W10O32]4- efficiently promoted the C(sp3)-H alkylation of the trifluoroacetic acid salt of valine methyl ester (H-Val-OMe·TFA) with electron-deficient alkenes under UV irradiation. The electrostatic interaction between the cationic ammonium group (+NH3) of… read more here.

Keywords: electrostatic interaction; alkylation; val residue; val ... See more keywords
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SOD2 gene polymorphism and response of oxidative stress parameters in young wrestlers to a three-month training

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recommendations! Published in 2017 at "Free Radical Research"

DOI: 10.1080/10715762.2017.1327716

Abstract: Abstract The aim of the study was to analyse the effect of Val 16Ala polymorphism in SOD2 gene on oxidative stress parameters and lipid profile of the blood during a three-month wrestling training. The study… read more here.

Keywords: sod2 gene; val; three month; activity ... See more keywords
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Improving performance of finishing pigs with added valine, isoleucine, and tryptophan: validating a meta-analysis model.

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recommendations! Published in 2021 at "Journal of animal science"

DOI: 10.1093/jas/skab006

Abstract: Based on results of a recent meta-analysis, we hypothesized that increased dietary Val, Ile, or Trp could correct possible amino acid interactions because of excess Leu in diets containing high levels of corn protein, namely… read more here.

Keywords: val; fed diets; val ile; pigs fed ... See more keywords