Synthesis and biological evaluation of Val–Val dipeptide–sulfonamide conjugates
Sign Up to like & getrecommendations! Published in 2020 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000074
Abstract: Novel Val–Val dipeptide–benzenesulfonamide conjugates were reported in this study. These were achieved by a condensation reaction of p‐substituted benzenesulfonamoyl alkanamides with 2‐amino‐4‐methyl‐N‐substituted phenyl butanamide using classical peptide‐coupling reagents. The compounds were characterized using Fourier transform… read more here.
Keywords: val dipeptide; biological evaluation; val; synthesis biological ... See more keywords
Isolation of high-purity peptide Val-Val-Tyr-Pro from Globin Peptide using MCI gel column combined with high-speed counter-current chromatography.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of separation science"
DOI: 10.1002/jssc.201800972
Abstract: Peptides have gained increased interest over the past several decades because of their therapeutics. In this research, a strategy combining MCI gel column chromatography and high-speed countercurrent chromatography was developed for the separation of high-purity… read more here.
Keywords: chromatography; val tyr; val; purity ... See more keywords
0043 BDNF Genotype Modulates Circadian Response to Simulated Nightwork in IL-6
Sign Up to like & getrecommendations! Published in 2020 at "Sleep"
DOI: 10.1093/sleep/zsaa056.042
Abstract: Brain Derived Neurotrophic Factor (BDNF) is involved in synaptic plasticity and may be involved in sleep and circadian regulation. The BDNF gene has a single nucleotide polymorphism (Val66Met) resulting in decreased BDNF secretion. The Met… read more here.
Keywords: response; val; genotype; simulated nightwork ... See more keywords
Sex and BDNF Val66Met polymorphism matter for exercise-induced increase in neurogenesis and cognition in middle-aged mice
Sign Up to like & getrecommendations! Published in 2022 at "Hormones and Behavior"
DOI: 10.1101/2022.07.29.502070
Abstract: Females show greater benefits of exercise on cognition in both humans and rodents, which may be related to brain-derived neurotrophic factor (BDNF). A single nucleotide polymorphism (SNP), the Val66Met polymorphism, within the human BDNF gene,… read more here.
Keywords: bdnf val; val; val val; mice ... See more keywords
Abstract 1047: Novel roles for manganese superoxide dismutase polymorphisms in prostate cancer
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-1047
Abstract: Prostate Cancer is the most common non-cutaneous cancer and second leading cause of cancer related death in American men. Epithelial Mesenchymal Transition (EMT), a key event in prostate cancer metastasis, is a process in which… read more here.
Keywords: cancer; prostate cancer; ala ala; ala ... See more keywords