Association of the COMT Val108/158Met genotype with professional career and education: The Val-allele is more frequent in managers and in enterprising occupations
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DOI: 10.1016/j.paid.2017.05.002
Abstract: Abstract Catechol- O -methyl transferase (COMT) is a key player in neurotransmission by catecholamines, and the functional COMT Val108/158Met polymorphism is strongly related to prefrontal reactivity and to dopamine levels. As dopamine is a critically… read more here.
Keywords: enterprising occupations; val allele; comt val108; 158met genotype ... See more keywords
Fast sleep spindle density is associated with rs4680 (Val108/158Met) genotype of catechol-O-methyltransferase (COMT)
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DOI: 10.1093/sleep/zsy007
Abstract: Study Objectives Sleep spindles are a hallmark of NREM stage 2 sleep. Fast sleep spindles correlate with cognitive functioning and are reduced in schizophrenia. Although spindles are highly genetically determined, distinct genetic mechanisms influencing sleep… read more here.
Keywords: sleep spindle; spindle density; comt; val108 158met ... See more keywords
The role of COMT gene Val108/158Met polymorphism in suicidal behavior: systematic review and updated meta-analysis
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DOI: 10.2147/ndt.s172243
Abstract: Background It is accepted that there is a genetic factor that influences the risk of suicidal behavior. The catechol-O-methyltransferase (COMT) gene, especially the Val108/158Met polymorphism, has been associated with suicide; however, no conclusive outcome has… read more here.
Keywords: val108 158met; suicidal behavior; polymorphism; meta analysis ... See more keywords