The Correlation between Plasma Brain-derived Neurotrophic Factor and Cognitive Function in Bipolar Disorder is Modulated by the BDNF Val66Met Polymorphism
Sign Up to like & getrecommendations! Published in 2017 at "European Psychiatry"
DOI: 10.1016/j.eurpsy.2017.01.243
Abstract: Objectives Brain-derived neurotrophic factor (BDNF) may be involved in the pathogenesis of bipolar disorder (BD). The functional BDNF Val66Met polymorphism (rs6265) is associated with secretion of BDNF. The current study aimed to explore the correlation… read more here.
Keywords: plasma bdnf; correlation; bdnf val66met; val66met polymorphism ... See more keywords
Variations in the APOE allele or BDNF Val66Met polymorphism are not associated with changes in cognitive function following a tertiary education intervention in older adults: the Tasmanian Healthy Brain Project
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2017.03.028
Abstract: The apolipoprotein (APOE) ε4 allele and the Met variant of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism are associated with reduced cognitive function in older adults. The aim of this study was to examine the… read more here.
Keywords: function; apoe allele; bdnf val66met; cognitive function ... See more keywords
BDNF Val66Met polymorphism and posttraumatic stress symptoms in U.S. military veterans: Protective effect of physical exercise
Sign Up to like & getrecommendations! Published in 2019 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2018.10.011
Abstract: The Met allele of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with reduced levels of BDNF release, heightened hypothalamic-pituitary-adrenal axis reactivity, and impaired fear extinction. As a result, Met allele carriers may be… read more here.
Keywords: ptsd symptoms; bdnf val66met; allele carriers; met allele ... See more keywords
BDNF Val66Met polymorphism and internalizing behaviors after early mild traumatic brain injury.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neurotrauma"
DOI: 10.1089/neu.2019.6936
Abstract: BACKGROUND Pediatric traumatic brain injury (TBI) can lead to adverse emotional, social and behavioral consequences. However, post-TBI outcome is difficult to predict due to significant individual variability, likely reflecting a complex interaction between injury- and… read more here.
Keywords: traumatic brain; brain injury; polymorphism internalizing; val66met polymorphism ... See more keywords
The BDNF Val66Met polymorphism impacts victim's moral emotions following interpersonal transgression.
Sign Up to like & getrecommendations! Published in 2020 at "Scandinavian journal of psychology"
DOI: 10.1111/sjop.12678
Abstract: Immoral behaviors make individuals abominate and punish transgressors. Inspired by the associations between the Val66Met polymorphism of brain-derived neurotropic factor (BDNF) gene and emotional responses following negative events, we investigated whether this polymorphism was also… read more here.
Keywords: moral emotions; following interpersonal; bdnf val66met; val66met polymorphism ... See more keywords
Plasma BDNF Level in Major Depression: Biomarker of the Val66Met BDNF Polymorphism and of the Clinical Course in Met Carrier Patients
Sign Up to like & getrecommendations! Published in 2017 at "Neuropsychobiology"
DOI: 10.1159/000478862
Abstract: Aims: Despite the involvement of the brain-derived neurotrophic factor (BDNF) in the physiopathology of major depressive disorder (MDD), the coherence between the components of the BDNF pathway and their link with the clinical features of… read more here.
Keywords: plasma bdnf; bdnf val66met; val66met polymorphism; bdnf levels ... See more keywords
The Role of the BDNF Val66Met Polymorphism in Recovery of Aphasia After Stroke
Sign Up to like & getrecommendations! Published in 2017 at "Neurorehabilitation and Neural Repair"
DOI: 10.1177/1545968317723752
Abstract: Background. Brain-derived neurotrophic factor (BDNF) is assumed to play a role in mediating neuroplasticity after stroke. Carriers of the function-limiting Val66Met (rs6265) single nucleotide polymorphism (SNP) may have a downregulation in BDNF secretion, which may… read more here.
Keywords: recovery; bdnf val66met; poststroke aphasia; val66met polymorphism ... See more keywords
The Influence of Val66Met Polymorphism in Brain-Derived Neurotrophic Factor on Stroke Recovery Outcome: A Systematic Review and Meta-analysis
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DOI: 10.1177/15459683211014119
Abstract: Background and purpose. A single nucleotide polymorphism at nucleotide 196 (G/A) in the human brain-derived neurotrophic factor (BDNF) gene produces an amino acid substitution (valine to methionine) at codon 66(Val66Met). It is unclear whether carriers… read more here.
Keywords: recovery; brain derived; derived neurotrophic; neurotrophic factor ... See more keywords
Effects of the BDNF Val66Met polymorphism on functional status and disability in young stroke patients
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DOI: 10.1371/journal.pone.0237033
Abstract: Background and purpose The preponderance of evidence from recent studies in human subjects supports a negative effect of the BDNF Val66Met polymorphism on motor outcomes and motor recovery. However prior studies have generally reported the… read more here.
Keywords: disability; bdnf val66met; stroke patients; val66met polymorphism ... See more keywords
BDNF val66met Polymorphism Impairs Hippocampal Long-Term Depression by Down-Regulation of 5-HT3 Receptors
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2017.00306
Abstract: Brain-derived neurotrophic factor (BDNF) is a key regulator of neuronal plasticity and cognitive functions. BDNF val66met polymorphism, a human single-nucleotide polymorphism (SNP) in the pro-domain of BDNF gene, is associated with deficits in activity-dependent BDNF… read more here.
Keywords: long term; bdnf val66met; bdnf; val66met polymorphism ... See more keywords
Brain-derived neurotrophic factor Val66Met polymorphism modulates the effects of circadian desynchronization on activity and sleep in male mice
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.1013673
Abstract: Introduction Understanding how environmental interact challenges with genetic predispositions modulate health and wellbeing is an important area of biomedical research. Circadian rhythms play an important role in coordinating the multitude of cellular and tissue processes… read more here.
Keywords: val66met polymorphism; brain; mice; circadian desynchronization ... See more keywords