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Published in 2021 at "Journal of Heart and Lung Transplantation"
DOI: 10.1016/j.healun.2021.01.958
Abstract: Purpose Management of neutropenia, the main side effect of Valganciclovir, may affect final transplant results. The main objective of this study is to evaluate the safety of Valganciclovir in D+/R- patients. The secondary objectives are…
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Keywords:
lung;
transplant;
treatment;
valganciclovir ... See more keywords
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Published in 2017 at "Journal of Coordination Chemistry"
DOI: 10.1080/00958972.2016.1257790
Abstract: Abstract A new complex, [Cu(valcyte)2(NO3)2], in which valcyte served as a valganciclovir drug, was synthesized and characterized by different physicochemical methods. Optimization of ligand structures and their complexes with Cu2+ were performed by semi-empirical and…
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Keywords:
valcyte no3;
dna;
drug;
complex ... See more keywords
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2
Published in 2023 at "Expert review of clinical pharmacology"
DOI: 10.1080/17512433.2023.2181161
Abstract: INTRODUCTION Infants and immunocompromised children with cytomegalovirus (CMV) infection have significant morbidity and mortality. Ganciclovir (GCV) and its oral prodrug valganciclovir (VGCV) are the major antiviral options of choice for the prophylaxis and treatment of…
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Keywords:
infection;
drug monitoring;
therapeutic drug;
dosing regimens ... See more keywords
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Published in 2021 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofab436
Abstract: Abstract Background Valganciclovir is the most commonly used antiviral for cytomegalovirus (CMV) prophylaxis in solid organ transplant recipients. However, there are limited clinical outcomes-supported data available to guide valganciclovir dosing in patients on hemodialysis (HD).…
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Keywords:
valganciclovir 450;
450 times;
prophylaxis;
transplant recipients ... See more keywords
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Published in 2023 at "Clinical transplantation"
DOI: 10.1111/ctr.15041
Abstract: BACKGROUND Cytomegalovirus (CMV) is a common infection in abdominal transplant recipients (ATR). Prevention of CMV in the highest risk population (CMV IgG donor+/recipient-) is critical as CMV is associated with negative outcomes. Guideline recommended prophylactic…
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Keywords:
infection;
cmv infection;
reduced dosing;
cmv ... See more keywords
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Published in 2021 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13617
Abstract: In clinical practice, conversion from universal cytomegalovirus prophylaxis (CMV PPX) with valganciclovir (VGC) to targeted therapy (preemptive monitoring, PEM) is often pursued in the setting of leukopenia. It is unknown if this is an effective…
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Keywords:
preemptive monitoring;
conversion;
cytomegalovirus;
prophylaxis ... See more keywords
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Published in 2020 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02254-20
Abstract: Ganciclovir is indicated for curative or preventive treatment of cytomegalovirus (CMV) infections. This study aimed to characterize ganciclovir pharmacokinetics, following intravenous ganciclovir and oral valganciclovir administration, to optimize dosing schemes. ABSTRACT Ganciclovir is indicated for…
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Keywords:
oral valganciclovir;
population;
valganciclovir;
ganciclovir oral ... See more keywords
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Published in 2018 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-018-3493-y
Abstract: BackgroundCytomegalovirus (CMV) prophylaxis may prevent CMV indirect effects in renal transplant recipients. This study aimed to compare the efficacy of valganciclovir and valacyclovir prophylaxis for CMV after renal transplantation with the focus on chronic histologic…
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Keywords:
fibrosis;
group;
prophylaxis;
open label ... See more keywords
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Published in 2020 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-020-05579-2
Abstract: Background Cytomegalovirus retinitis (CMVR) is an opportunistic infection in HIV-infected people. Intraocular or intravenous ganciclovir was gold standard for treatment; however, oral valganciclovir replaced this in high-income countries. Low- and middle-income countries (LMIC) frequently use…
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Keywords:
treatment;
hiv;
cytomegalovirus retinitis;
valganciclovir ... See more keywords
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1
Published in 2022 at "Cancers"
DOI: 10.3390/cancers14081958
Abstract: Simple Summary Patients with glioblastoma have a dismal prognosis. The major challenge with this disease is that it recurs despite aggressive first-line therapy and rapidly becomes therapy resistant. Cytomegalovirus has been found in most glioblastoma…
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Keywords:
therapy;
recurrent glioblastoma;
valganciclovir;
patients recurrent ... See more keywords
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Published in 2022 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_2787_21
Abstract: Purpose: To study clinical efficacy of valganciclovir in cytomegalovirus retinitis (CMVR) in human immunodeficiency virus (HIV)-positive-positive patients in a tertiary care clinic in a developing nation. Methods: In a retrospective study, systemic and ocular records…
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Keywords:
cytomegalovirus retinitis;
positive patients;
immunodeficiency virus;
tertiary care ... See more keywords