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   Articles with "valganciclovir" as a keyword



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Tolerance of Anti-CMV Prophylaxis with Valganciclovir One-Year Treatment in D+/R- Lung Transplant Patients. A Single-Center Retrospective Study

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recommendations! Published in 2021 at "Journal of Heart and Lung Transplantation"

DOI: 10.1016/j.healun.2021.01.958

Abstract: Purpose Management of neutropenia, the main side effect of Valganciclovir, may affect final transplant results. The main objective of this study is to evaluate the safety of Valganciclovir in D+/R- patients. The secondary objectives are… read more here.

Keywords: lung; transplant; treatment; valganciclovir ... See more keywords
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Synthesis, characterization and in vitro DNA binding studies of a new copper(II) complex containing an antiviral drug, valganciclovir

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recommendations! Published in 2017 at "Journal of Coordination Chemistry"

DOI: 10.1080/00958972.2016.1257790

Abstract: Abstract A new complex, [Cu(valcyte)2(NO3)2], in which valcyte served as a valganciclovir drug, was synthesized and characterized by different physicochemical methods. Optimization of ligand structures and their complexes with Cu2+ were performed by semi-empirical and… read more here.

Keywords: valcyte no3; dna; drug; complex ... See more keywords
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Optimizing ganciclovir and valganciclovir dosing regimens in pediatric patients with cytomegalovirus infection: a spotlight on therapeutic drug monitoring.

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recommendations! Published in 2023 at "Expert review of clinical pharmacology"

DOI: 10.1080/17512433.2023.2181161

Abstract: INTRODUCTION Infants and immunocompromised children with cytomegalovirus (CMV) infection have significant morbidity and mortality. Ganciclovir (GCV) and its oral prodrug valganciclovir (VGCV) are the major antiviral options of choice for the prophylaxis and treatment of… read more here.

Keywords: infection; drug monitoring; therapeutic drug; dosing regimens ... See more keywords
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Safety of Valganciclovir 450 mg 3 Times Weekly for Cytomegalovirus Prophylaxis in Solid Organ Transplant Recipients Requiring Hemodialysis

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recommendations! Published in 2021 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofab436

Abstract: Abstract Background Valganciclovir is the most commonly used antiviral for cytomegalovirus (CMV) prophylaxis in solid organ transplant recipients. However, there are limited clinical outcomes-supported data available to guide valganciclovir dosing in patients on hemodialysis (HD).… read more here.

Keywords: valganciclovir 450; 450 times; prophylaxis; transplant recipients ... See more keywords
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Reduced dosing versus full dosing valganciclovir for prophylaxis of cytomegalovirus in high-risk abdominal transplant recipients.

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recommendations! Published in 2023 at "Clinical transplantation"

DOI: 10.1111/ctr.15041

Abstract: BACKGROUND Cytomegalovirus (CMV) is a common infection in abdominal transplant recipients (ATR). Prevention of CMV in the highest risk population (CMV IgG donor+/recipient-) is critical as CMV is associated with negative outcomes. Guideline recommended prophylactic… read more here.

Keywords: infection; cmv infection; reduced dosing; cmv ... See more keywords

Conversion from cytomegalovirus universal prophylaxis with valganciclovir to the preemptive monitoring approach to manage leukopenia after kidney or pancreas transplantation

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recommendations! Published in 2021 at "Transplant Infectious Disease"

DOI: 10.1111/tid.13617

Abstract: In clinical practice, conversion from universal cytomegalovirus prophylaxis (CMV PPX) with valganciclovir (VGC) to targeted therapy (preemptive monitoring, PEM) is often pursued in the setting of leukopenia. It is unknown if this is an effective… read more here.

Keywords: preemptive monitoring; conversion; cytomegalovirus; prophylaxis ... See more keywords
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Population Pharmacokinetics of Intravenous Ganciclovir and Oral Valganciclovir in a Pediatric Population To Optimize Dosing Regimens

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recommendations! Published in 2020 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.02254-20

Abstract: Ganciclovir is indicated for curative or preventive treatment of cytomegalovirus (CMV) infections. This study aimed to characterize ganciclovir pharmacokinetics, following intravenous ganciclovir and oral valganciclovir administration, to optimize dosing schemes. ABSTRACT Ganciclovir is indicated for… read more here.

Keywords: oral valganciclovir; population; valganciclovir; ganciclovir oral ... See more keywords
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Less renal allograft fibrosis with valganciclovir prophylaxis for cytomegalovirus compared to high-dose valacyclovir: a parallel group, open-label, randomized controlled trial

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recommendations! Published in 2018 at "BMC Infectious Diseases"

DOI: 10.1186/s12879-018-3493-y

Abstract: BackgroundCytomegalovirus (CMV) prophylaxis may prevent CMV indirect effects in renal transplant recipients. This study aimed to compare the efficacy of valganciclovir and valacyclovir prophylaxis for CMV after renal transplantation with the focus on chronic histologic… read more here.

Keywords: fibrosis; group; prophylaxis; open label ... See more keywords
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Treating HIV-associated cytomegalovirus retinitis with oral valganciclovir and intra-ocular ganciclovir by primary HIV clinicians in southern Myanmar: a retrospective analysis of routinely collected data

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recommendations! Published in 2020 at "BMC Infectious Diseases"

DOI: 10.1186/s12879-020-05579-2

Abstract: Background Cytomegalovirus retinitis (CMVR) is an opportunistic infection in HIV-infected people. Intraocular or intravenous ganciclovir was gold standard for treatment; however, oral valganciclovir replaced this in high-income countries. Low- and middle-income countries (LMIC) frequently use… read more here.

Keywords: treatment; hiv; cytomegalovirus retinitis; valganciclovir ... See more keywords

Valganciclovir as Add-on to Second-Line Therapy in Patients with Recurrent Glioblastoma

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recommendations! Published in 2022 at "Cancers"

DOI: 10.3390/cancers14081958

Abstract: Simple Summary Patients with glioblastoma have a dismal prognosis. The major challenge with this disease is that it recurs despite aggressive first-line therapy and rapidly becomes therapy resistant. Cytomegalovirus has been found in most glioblastoma… read more here.

Keywords: therapy; recurrent glioblastoma; valganciclovir; patients recurrent ... See more keywords
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Oral valganciclovir in human immunodeficiency virus-positive patients suffering from cytomegalovirus retinitis at a tertiary care hospital in North India

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recommendations! Published in 2022 at "Indian Journal of Ophthalmology"

DOI: 10.4103/ijo.ijo_2787_21

Abstract: Purpose: To study clinical efficacy of valganciclovir in cytomegalovirus retinitis (CMVR) in human immunodeficiency virus (HIV)-positive-positive patients in a tertiary care clinic in a developing nation. Methods: In a retrospective study, systemic and ocular records… read more here.

Keywords: cytomegalovirus retinitis; positive patients; immunodeficiency virus; tertiary care ... See more keywords