Articles with "valganciclovir toxicity" as a keyword



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Novel risk factor for valganciclovir toxicity—NUDT15 genetic variant

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Published in 2022 at "Transplant Infectious Disease"

DOI: 10.1111/tid.13799

Abstract: Recent “in vitro” studies describe nucleoside diphosphate–linked moiety X-type motif 15 (NUDT15) enzyme to be involved in the metabolismofganciclovir. 1,2 Wereportsevereleukopeniaduringther-apy with valganciclovir in a recent kidney transplant recipient with NUDT15 geneticvariation.Thiscasereportisthefirsttosubstantiatea theoretical postulate of… read more here.

Keywords: factor valganciclovir; toxicity nudt15; valganciclovir toxicity; risk factor ... See more keywords