Alkaline pH shock enhanced production of validamycin A in fermentation of Streptomyces hygroscopicus.
Sign Up to like & getrecommendations! Published in 2018 at "Bioresource technology"
DOI: 10.1016/j.biortech.2017.10.012
Abstract: Validamycin A (Val-A) is produced by Streptomyces as a secondary metabolite with wide agricultural applications of controlling rice sheath blight, false smut and damping-off diseases. The effect of alkaline pH shock on enhancing Val-A production… read more here.
Keywords: production; alkaline shock; val production; validamycin ... See more keywords
Suppressing the activity of trehalase with validamycin disrupts the trehalose and chitin biosynthesis pathways in the rice brown planthopper, Nilaparvata lugens.
Sign Up to like & getrecommendations! Published in 2017 at "Pesticide biochemistry and physiology"
DOI: 10.1016/j.pestbp.2016.10.003
Abstract: Trehalase (TRE) is a key enzyme in trehalose degradation and has important functions in insect growth and chitin synthesis. Though validamycin has the potential for pest control by suppressing TRE activities, it is not known… read more here.
Keywords: insects; control; trehalose chitin; expression ... See more keywords