Articles with "validate surrogate" as a keyword



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Incorporating baseline covariates to validate surrogate endpoints with a constant biomarker under control arm.

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Published in 2021 at "Statistics in medicine"

DOI: 10.1002/sim.9201

Abstract: A surrogate endpoint S in a clinical trial is an outcome that may be measured earlier or more easily than the true outcome of interest T. In this work, we extend causal inference approaches to… read more here.

Keywords: validate surrogate; potential outcomes; surrogate; incorporating baseline ... See more keywords