A sensitive and validated LC-MS/MS method for high-throughput determination of pomalidomide in human plasma and pharmacokinetic studies
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.07.009
Abstract: ABSTRACT Pomalidomide is an immunomodulatory agent (IMiD) that has been approved by the Food and Drug Administration (FDA) for clinical treatment of patients with multiple myeloma. In this work, we developed a sensitive and validated… read more here.
Keywords: sensitive validated; method high; validated method; high throughput ... See more keywords
Validated Method for the Screening and Quantification of Baclofen, Gabapentin and Pregabalin in Human Post-Mortem Whole Blood Using Protein Precipitation and Liquid Chromatography-Tandem Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkx019
Abstract: There has been a rapid increase in the number of prescriptions for baclofen (BLF), gabapentin (GBP) and pregabalin (PGL) in the UK since their introduction to therapy. Recent studies across the European Union and USA… read more here.
Keywords: gbp; blood; validated method; pgl ... See more keywords
A Validated Method for the Screening of 320 Forensically Significant Compounds in Blood by LC/QTOF, with Simultaneous Quantification of Selected Compounds.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkx108
Abstract: A broad drug screening method for toxicologically significant drugs and metabolites in whole blood using liquid chromatography time-of-flight mass spectrometry (LC/QTOF) was developed and comprehensively validated. The method qualitatively screens for 320 compounds while simultaneously… read more here.
Keywords: screening 320; method screening; method; blood ... See more keywords
A Pharmacokinetic Study of Ephedrine and Pseudoephedrine after Oral Administration of Ojeok-San by Validated LC-MS/MS Method in Human Plasma
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26226991
Abstract: A sensitive and reproducible liquid chromatography-tandem mass spectrometry (LC-MS/MS) system was developed and fully validated for the simultaneous determination of ephedrine and pseudoephedrine in human plasma after oral administration of the herbal prescription Ojeok-san (OJS);… read more here.
Keywords: administration; human plasma; ephedrine pseudoephedrine; validated method ... See more keywords
A Validated Method for the Simultaneous Determination of Oxytocin and Cortisol in Human Saliva
Sign Up to like & getrecommendations! Published in 2024 at "Separations"
DOI: 10.3390/separations11080240
Abstract: Oxytocin and cortisol (OXY and CORT) are hormones related to stress, cognitive, and social behaviors. Their detection is relevant to epidemiological studies aimed at investigating the effects of stressor factors on human life. The aim… read more here.
Keywords: saliva; oxytocin cortisol; method simultaneous; validated method ... See more keywords
A New Advanced and Validated Method for the Determination of Potentially Toxic Metals and Trace and Ultra-Trace Elements in Peritoneal Fluid to Assess the Health Risks of Women with Gynecological Pathologies
Sign Up to like & getrecommendations! Published in 2023 at "Toxics"
DOI: 10.3390/toxics11050399
Abstract: Toxic metals found in the environment have been linked to female infertility and gynecological illnesses. Reliable analytical methods, such as inductively coupled plasma tandem mass spectrometry (ICP-MS/MS), are necessary to determine the elemental composition of… read more here.
Keywords: new advanced; advanced validated; validated method; toxic metals ... See more keywords