Articles with "validation" as a keyword



A Simple Score to Identify Increased Risk of Transthyretin Amyloid Cardiomyopathy in Heart Failure With Preserved Ejection Fraction.

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Published in 2022 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2022.1781

Abstract: Importance Transthyretin amyloid cardiomyopathy (ATTR-CM) is a form of heart failure (HF) with preserved ejection fraction (HFpEF). Technetium Tc 99m pyrophosphate scintigraphy (PYP) enables ATTR-CM diagnosis. It is unclear which patients with HFpEF have sufficient… read more here.

Keywords: validation; prevalence; ejection fraction; risk ... See more keywords

Deep Learning-Augmented ECG Analysis for Screening and Genotype Prediction of Congenital Long QT Syndrome.

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Published in 2024 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2024.0039

Abstract: Importance Congenital long QT syndrome (LQTS) is associated with syncope, ventricular arrhythmias, and sudden death. Half of patients with LQTS have a normal or borderline-normal QT interval despite LQTS often being detected by QT prolongation… read more here.

Keywords: deep learning; validation; lqts; congenital long ... See more keywords

Diagnosis uPGrade-Advances in Pyoderma Gangrenosum.

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Published in 2018 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2017.5979

Abstract: In this issue of JAMA Dermatology, 2 large, well-constructed studies remind dermatologists that even though pyoderma gangrenosum (PG) is a quintessential disease in medical dermatology, we still need data to better define the disease and… read more here.

Keywords: validation; dermatology; diagnosis; disease ... See more keywords

Development and Validation of a Patient-Reported Outcome Measure to Assess Disease Control in Chronic Prurigo.

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Published in 2024 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2023.5519

Abstract: Importance Chronic prurigo (CPG), including prurigo nodularis, is a difficult disease to treat and considerably affects patients' quality of life. Helping patients obtain control of CPG is a major treatment goal. Objective To develop and… read more here.

Keywords: disease; pct; control; disease control ... See more keywords
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Identification and Validation of Plasma Metabolomic Signatures in Precancerous Gastric Lesions That Progress to Cancer.

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Published in 2021 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2021.14186

Abstract: Importance Metabolic deregulation plays an important role in gastric cancer (GC) development. To date, no studies have comprehensively explored the metabolomic profiles along the cascade of gastric lesions toward GC. Objective To draw a metabolic… read more here.

Keywords: gastric lesions; risk; validation; metabolomic signatures ... See more keywords

Development and Validation of a Deep Learning Model to Predict the Occurrence and Severity of Retinopathy of Prematurity.

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Published in 2022 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2022.17447

Abstract: Importance Retinopathy of prematurity (ROP) is the leading cause of childhood blindness worldwide. Prediction of ROP before onset holds great promise for reducing the risk of blindness. Objective To develop and validate a deep learning… read more here.

Keywords: rop; validation; severity; deep learning ... See more keywords

Development and Methodological Validation of a Modified Staging System for de Novo Metastatic Breast Cancer

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Published in 2024 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2024.2174

Abstract: This cohort study performs an external validation of a novel system for understanding outcomes of de novo metastatic breast cancer. read more here.

Keywords: novo metastatic; breast cancer; system; metastatic breast ... See more keywords

Development and Validation of an Individualized Immune Prognostic Signature in Early-Stage Nonsquamous Non–Small Cell Lung Cancer

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Published in 2017 at "JAMA Oncology"

DOI: 10.1001/jamaoncol.2017.1609

Abstract: Importance The prevalence of early-stage non–small cell lung cancer (NSCLC) is expected to increase with recent implementation of annual screening programs. Reliable prognostic biomarkers are needed to identify patients at a high risk for recurrence… read more here.

Keywords: validation; nonsquamous nsclc; early stage; signature ... See more keywords

Development and Validation of a Novel Acute Myeloid Leukemia–Composite Model to Estimate Risks of Mortality

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Published in 2017 at "JAMA Oncology"

DOI: 10.1001/jamaoncol.2017.2714

Abstract: Importance To our knowledge, this multicenter analysis is the first to test and validate (1) the prognostic impact of comorbidities on 1-year mortality after initial therapy of acute myeloid leukemia (AML) and (2) a novel,… read more here.

Keywords: validation; year; mortality; composite model ... See more keywords
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Development and Validation of a Clinical Prognostic Stage Group System for Nonmetastatic Prostate Cancer Using Disease-Specific Mortality Results From the International Staging Collaboration for Cancer of the Prostate.

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Published in 2020 at "JAMA oncology"

DOI: 10.1001/jamaoncol.2020.4922

Abstract: Importance In 2016, the American Joint Committee on Cancer (AJCC) established criteria to evaluate prediction models for staging. No localized prostate cancer models were endorsed by the Precision Medicine Core committee, and 8th edition staging… read more here.

Keywords: prostate; system; validation; prostate cancer ... See more keywords

Derivation and Validation of Predictive Models for Early Pediatric Sepsis.

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Published in 2025 at "JAMA pediatrics"

DOI: 10.1001/jamapediatrics.2025.3892

Abstract: Importance Sepsis is a leading cause of death in children. Early recognition and treatment improve outcomes, but predictive models have not to date improved early diagnosis. Objective To develop machine learning models to estimate the… read more here.

Keywords: predictive models; validation; shock; sepsis ... See more keywords