A Simple Score to Identify Increased Risk of Transthyretin Amyloid Cardiomyopathy in Heart Failure With Preserved Ejection Fraction.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.1781
Abstract: Importance Transthyretin amyloid cardiomyopathy (ATTR-CM) is a form of heart failure (HF) with preserved ejection fraction (HFpEF). Technetium Tc 99m pyrophosphate scintigraphy (PYP) enables ATTR-CM diagnosis. It is unclear which patients with HFpEF have sufficient… read more here.
Keywords: validation; prevalence; ejection fraction; risk ... See more keywords
Diagnosis uPGrade-Advances in Pyoderma Gangrenosum.
Sign Up to like & getrecommendations! Published in 2018 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2017.5979
Abstract: In this issue of JAMA Dermatology, 2 large, well-constructed studies remind dermatologists that even though pyoderma gangrenosum (PG) is a quintessential disease in medical dermatology, we still need data to better define the disease and… read more here.
Keywords: validation; dermatology; diagnosis; disease ... See more keywords
Identification and Validation of Plasma Metabolomic Signatures in Precancerous Gastric Lesions That Progress to Cancer.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2021.14186
Abstract: Importance Metabolic deregulation plays an important role in gastric cancer (GC) development. To date, no studies have comprehensively explored the metabolomic profiles along the cascade of gastric lesions toward GC. Objective To draw a metabolic… read more here.
Keywords: gastric lesions; risk; validation; metabolomic signatures ... See more keywords
Development and Validation of a Deep Learning Model to Predict the Occurrence and Severity of Retinopathy of Prematurity.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2022.17447
Abstract: Importance Retinopathy of prematurity (ROP) is the leading cause of childhood blindness worldwide. Prediction of ROP before onset holds great promise for reducing the risk of blindness. Objective To develop and validate a deep learning… read more here.
Keywords: rop; validation; severity; deep learning ... See more keywords
Development and Validation of an Individualized Immune Prognostic Signature in Early-Stage Nonsquamous Non–Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.1609
Abstract: Importance The prevalence of early-stage non–small cell lung cancer (NSCLC) is expected to increase with recent implementation of annual screening programs. Reliable prognostic biomarkers are needed to identify patients at a high risk for recurrence… read more here.
Keywords: validation; nonsquamous nsclc; early stage; signature ... See more keywords
Development and Validation of a Novel Acute Myeloid Leukemia–Composite Model to Estimate Risks of Mortality
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.2714
Abstract: Importance To our knowledge, this multicenter analysis is the first to test and validate (1) the prognostic impact of comorbidities on 1-year mortality after initial therapy of acute myeloid leukemia (AML) and (2) a novel,… read more here.
Keywords: validation; year; mortality; composite model ... See more keywords
Development and Validation of a Clinical Prognostic Stage Group System for Nonmetastatic Prostate Cancer Using Disease-Specific Mortality Results From the International Staging Collaboration for Cancer of the Prostate.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2020.4922
Abstract: Importance In 2016, the American Joint Committee on Cancer (AJCC) established criteria to evaluate prediction models for staging. No localized prostate cancer models were endorsed by the Precision Medicine Core committee, and 8th edition staging… read more here.
Keywords: prostate; system; validation; prostate cancer ... See more keywords
An Investigation of Psychosis Subgroups With Prognostic Validation and Exploration of Genetic Underpinnings: The PsyCourse Study.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2019.4910
Abstract: Importance Identifying psychosis subgroups could improve clinical and research precision. Research has focused on symptom subgroups, but there is a need to consider a broader clinical spectrum, disentangle illness trajectories, and investigate genetic associations. Objective… read more here.
Keywords: illness courses; psychosis subgroups; validation; disorder ... See more keywords
Ultrasensitive NIR‐SERRS Probes with Multiplexed Ratiometric Quantification for In Vivo Antibody Leads Validation
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201700870
Abstract: Immunotargeting ability of antibodies may show significant difference between in vitro and in vivo. To select antibody leads with high affinity and specificity, it is necessary to perform in vivo validation of antibody candidates following… read more here.
Keywords: validation; vivo; nir serrs; antibody ... See more keywords
A multicontinuum approach for the problem of filtration of oily‐water systems across thin flat membranes: II. Validation and examples
Sign Up to like & getrecommendations! Published in 2018 at "Aiche Journal"
DOI: 10.1002/aic.15970
Abstract: In this second part, a validation exercise is conducted to investigate the accuracy of the multicontinuum approach in estimating the permeation capacity of membranes used for the filtration of oily-water systems. Comparisons with the experimental… read more here.
Keywords: validation; oily water; multicontinuum approach; filtration oily ... See more keywords
Radial diffusion model for fragrance materials: Prediction and validation
Sign Up to like & getrecommendations! Published in 2021 at "Aiche Journal"
DOI: 10.1002/aic.17351
Abstract: A predictive model based on Fick’s second law for radial diffusion is proposed and validated for modeling the diffusion of fragrances. A pure component, two binary systems, and a ternary system were used for validation.… read more here.
Keywords: validation; radial diffusion; fragrance; diffusion ... See more keywords