Discovery and Validation of Clinical Biomarkers of Cancer: A Review Combining Metabolomics and Proteomics
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DOI: 10.1002/pmic.201700448
Abstract: Early detection and diagnosis of cancer can allow timely medical intervention, which greatly improves chances of survival and enhances quality of life. Biomarkers play an important role in assisting clinicians and health care providers in… read more here.
Keywords: validation; validation clinical; review; cancer ... See more keywords
Erratum to: External validation of clinical decision rules for children with wrist trauma
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DOI: 10.1007/s00247-017-3841-x
Abstract: The published version of this article contained mistakes. Table 6 was published with incorrect table heading and table legend. This has now been corrected. read more here.
Keywords: erratum external; external validation; decision rules; validation clinical ... See more keywords
Development and validation of a clinical assessment tool for postgraduate nursing education: A consensus-group study.
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DOI: 10.1016/j.nepr.2020.102741
Abstract: Postgraduate education programmes in health professions need to assess their students’ ability to practise in relation to the expected standards and to verify that students have met certain criteri ... read more here.
Keywords: clinical assessment; tool postgraduate; development validation; assessment tool ... See more keywords
The Cauda Scale – Validation for Clinical Practice
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DOI: 10.1080/02688697.2020.1754337
Abstract: Abstract Purpose: The purpose of this study was to validate the cauda scale (TCS) in an external population. TCS was proposed as a tool to be used to predict the likelihood of cauda equina compression.… read more here.
Keywords: clinical practice; validation clinical; cauda scale; cauda equina ... See more keywords
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia
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DOI: 10.1111/jth.15885
Abstract: Immune thrombocytopenia (ITP) is a diagnosis of exclusion that can resemble other thrombocytopenic disorders. read more here.
Keywords: immune thrombocytopenia; internal validation; diagnosis; validation clinical ... See more keywords
Abstract 4758: Use of highly multiplexed reference materials to facilitate validation of a clinical NGS tumor fusion RNA assay
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DOI: 10.1158/1538-7445.am2018-4758
Abstract: Introduction: Next Generation Sequencing assays for detection of tumor RNA fusions must undergo rigorous validation before clinical implementation. Validations include assessment of the assay9s accuracy, precision, reproducibility and limits of detection or reportable range. Obtaining… read more here.
Keywords: detection; reference materials; validation; validation clinical ... See more keywords
Validation and clinical application of transactivation assays for RUNX1 variant classification
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DOI: 10.1182/bloodadvances.2021006161
Abstract: Key Points Transactivation assays are appropriate for functional characterization of the majority of RUNX1 missense variants observed in RUNX1-FPD. Implementation of transactivation assays for RUNX1 variants with unknown function accelerates their translation into clinical care. read more here.
Keywords: transactivation; clinical application; validation clinical; application transactivation ... See more keywords
Development and validation of a clinical instrument to predict risk of an adverse drug reactions in hospitalized patients
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DOI: 10.1371/journal.pone.0243714
Abstract: Objective Development and internal validation of a clinical tool for assessment of the risk of adverse drug reactions (ADR) in hospitalized patients. Methodology Nested case-control study in an open cohort of all patients admitted to… read more here.
Keywords: risk; validation clinical; risk adverse; adverse drug ... See more keywords
Construction and validation of clinical contents for development of learning objects.
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DOI: 10.1590/0034-7167-2016-0622
Abstract: OBJECTIVE to describe the process of construction and validation of clinical contents for health learning objects, aimed at patients in the treatment of head and neck cancer. METHOD descriptive, methodological study. The development of the… read more here.
Keywords: construction; validation clinical; clinical contents; learning objects ... See more keywords
Validation of a clinical simulation setting in the management of postpartum haemorrhage.
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DOI: 10.1590/0034-7167-2018-0065
Abstract: OBJECTIVE To construct and validate a clinical simulation setting for postpartum haemorrhage. METHOD Quantitative research of methodological development, carried out from May to July of 2016 with 22 expert judges and 30 students. Analysis was… read more here.
Keywords: simulation setting; clinical simulation; validation clinical; postpartum haemorrhage ... See more keywords
Development and validation of a clinical prediction model to estimate the probability of malignancy in solid pancreatic lesions and explore its value in the atypical diagnostic category after endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA)
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DOI: 10.21037/tcr-20-2208
Abstract: Medical School of Southeast University, Nanjing, China; Department of Gastroenterology, Southeast University Affiliated Zhongda Hospital, Nanjing, China Contributions: (I) Conception and design: N Wei; (II) Administrative support: RH Shi; (III) Provision of study materials or… read more here.
Keywords: development validation; validation clinical; gastroenterology; clinical prediction ... See more keywords